Methotrexate

甲氨蝶呤

Also known as: Amethopterin, MTX, 4-Amino-10-methylfolic acid, 4-Amino-N10-methylpteroylglutamic acid, L-Amethopterin, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid, (+)-Amethopterin, 4-Amino-4-deoxy-10-methylpteroyl-L-glutamic acid, L-(+)-N-[p-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]glutamic Acid, Mexate

Methotrexate (CAS 59-05-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H22N8O5 and a molecular weight of 454.439 g/mol. It is also known as Amethopterin, MTX and 4-Amino-10-methylfolic acid. Key properties include a melting point of 195°C, a boiling point of 561.26°C, a density of 1.4080 and a flash point of 11℃. GHS signal word: Danger. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
59-05-2
Jingsj CID
J-1014813-8
Molecular Formula
C20H22N8O5
Chinese Name
甲氨蝶呤
Molecular Weight
454.439 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point195°C
Boiling Point561.26°C
Density1.4080
Flash Point11℃

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger

Frequently Asked Questions

What is the CAS number of Methotrexate?

The CAS number of Methotrexate is 59-05-2.

What are the molecular formula and molecular weight of Methotrexate?

Methotrexate has molecular formula C20H22N8O5 and molecular weight 454.439 g/mol.

Is Methotrexate hazardous?

Methotrexate has GHS signal word Danger.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Methotrexate (CAS 59-05-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1014813-8 (accessed 2026-10-22).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.