Licochalcone A
甘草查尔酮A
Also known as: (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one, (2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one, LICOCHALCONE-A, 4′,4-Dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone, 5-(1,1-dimethylallyl)-4,4′-dihydroxy-2-methoxychalcone
Licochalcone A (CAS 58749-22-7) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H22O4 and a molecular weight of 338.397 g/mol. It is also known as (E)-3-[4-hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one, (2E)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one and LICOCHALCONE-A. Key properties include a melting point of 100°, a boiling point of 532.6±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 186.9±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 58749-22-7
- Jingsj CID
- J-35960-3
- Molecular Formula
- C21H22O4
- Chinese Name
- 甘草查尔酮A
- Molecular Weight
- 338.397 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 100° |
|---|---|
| Boiling Point | 532.6±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 186.9±23.6 °C |
| Exact Mass | 338.151794 |
| PSA | 66.76000 |
| LogP | 4.95 |
| Vapor Pressure | 0.0±1.5 mmHg at 25°C |
| Refractive Index | 1.611 |
Activity & Biological Data
| Additional Information | [1]. Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241. [2]. Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical ToxicologyVolume 90, April 2016, Pages 112–122 [3]. Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70. |
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Frequently Asked Questions
What is the CAS number of Licochalcone A?
The CAS number of Licochalcone A is 58749-22-7.
What are the molecular formula and molecular weight of Licochalcone A?
Licochalcone A has molecular formula C21H22O4 and molecular weight 338.397 g/mol.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Licochalcone A (CAS 58749-22-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-35960-3 (accessed 2026-10-29).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.