Higenamine
去甲乌药碱
Also known as: Norcoclaurine, (±)-Higenamine, rac-norcoclaurine, 1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol, 1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol, 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, Demethylcoclaurine, (±)-Demethylcoclaurine, (R,S)-norcoclaurine, Coclaurine, O-demethyl-, (±)-, DL-Demethylcoclaurine, UNII:TBV5O16GAP
Higenamine (CAS 5843-65-2) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C16H17NO3 and a molecular weight of 271.311 g/mol. It is also known as Norcoclaurine, (±)-Higenamine and rac-norcoclaurine. Key properties include a melting point of 208-210℃, a boiling point of 522.4±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 209.6±20.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 5843-65-2
- Jingsj CID
- J-1971120-1
- Molecular Formula
- C16H17NO3
- Chinese Name
- 去甲乌药碱
- Molecular Weight
- 271.311 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 208-210℃ |
|---|---|
| Boiling Point | 522.4±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 209.6±20.7 °C |
| Exact Mass | 271.120850 |
| PSA | 72.72000 |
| LogP | 1.41 |
| Vapor Pressure | 0.0±1.4 mmHg at 25°C |
| Refractive Index | 1.666 |
Activity & Biological Data
| Target | β2-AR[1] |
|---|---|
| Additional Information | [1]. Wu MP, et al. Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway. Pharmacol Res. 2016 Feb;104:115-23. [2]. Lee SR, et al. Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acidsand energy expenditure in human subjects. Lipids Health Dis. 2013 Oct 21;12:148. |
Frequently Asked Questions
What is the CAS number of Higenamine?
The CAS number of Higenamine is 5843-65-2.
What are the molecular formula and molecular weight of Higenamine?
Higenamine has molecular formula C16H17NO3 and molecular weight 271.311 g/mol.
What are the upstream and downstream products of Higenamine?
For Higenamine, Upstream Products: Dopamine, 2-(4-Hydroxyphenyl)acetaldehyde, (3,4-Dimethoxyphenyl)acetic acid.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Higenamine (CAS 5843-65-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1971120-1 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.