Puromycin aminonucleoside

嘌呤霉素氨基核苷

Also known as: Stylomycin aminonucleoside, 3'-Amino-3'-deoxy-N,N-dimethyladenosine, 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine, 3'-amino-3'-deoxy-N6,N6-dimethyladenosine, 9-(3-Amino-3-deoxy-β-D-ribofuranosyl)-N,N-dimethyl-9H-purin-6-amine, Adenosine, 3'-amino-3'-deoxy-N,N-dimethyl-, Puromycin aminonucleoside, Aminonucleoside puromycin

Puromycin aminonucleoside (CAS 58-60-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C12H18N6O3 and a molecular weight of 294.310 g/mol. It is also known as Stylomycin aminonucleoside, 3'-Amino-3'-deoxy-N,N-dimethyladenosine and 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine. Key properties include a melting point of 235℃ (Decomposition), a boiling point of 595.6±60.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 314.0±32.9 °C. It is classified under GHS with signal word Warning and hazard statements H373 — May cause damage to organs through prolonged exposure. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
58-60-6
Jingsj CID
J-3636-8
Molecular Formula
C12H18N6O3
Chinese Name
嘌呤霉素氨基核苷
Molecular Weight
294.310 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point235℃ (Decomposition)
Boiling Point595.6±60.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point314.0±32.9 °C
Exact Mass294.144043
PSA122.55000
LogP0.02
Vapor Pressure0.0±1.8 mmHg at 25°C
Refractive Index1.776
Additional PropertyH2O: 50 mg/mL, clear, slightly yellow | Soluble in water at 50mg/ml. May require heating

GHS Safety & Compliance

Health HazardSignal word: Warning
  • H373 — May cause damage to organs through prolonged exposure

Activity & Biological Data

Additional Information[1]. Wada T, et al. Dexamethasone prevents podocyte apoptosis induced by puromycin aminonucleoside: role of p53 and Bcl-2-related family proteins. J Am Soc Nephrol. 2005 Sep;16(9):2615-25. [2]. Xia L, et al. Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleosidenephrotoxicity. Am J Physiol Renal Physiol. 2009 Jun;296(6):F1307-13. [3]. Kawakami H, et al. Dynamics of absolute amount of nephrin in a single podocyte in puromycin aminonucleoside nephrosis rats calculated by quantitative glomerular proteomics approach with selected reaction monitoring mode. Nephrol Dial Transplant. 2012 Apr; [4]. Nosaka K, et al. An adenosine deaminase inhibitor prevents puromycin aminonucleoside nephrotoxicity. Free Radic Biol Med 1997 ;22 (4): 597-605.

Frequently Asked Questions

What is the CAS number of Puromycin aminonucleoside?

The CAS number of Puromycin aminonucleoside is 58-60-6.

What are the molecular formula and molecular weight of Puromycin aminonucleoside?

Puromycin aminonucleoside has molecular formula C12H18N6O3 and molecular weight 294.310 g/mol.

Is Puromycin aminonucleoside hazardous?

Puromycin aminonucleoside has GHS signal word Warning and hazard statements H373 — May cause damage to organs through prolonged exposure.

What are the upstream and downstream products of Puromycin aminonucleoside?

For Puromycin aminonucleoside, Downstream Products: Puromycin.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Puromycin aminonucleoside (CAS 58-60-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3636-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.