Idarubicin hydrochloride

盐酸伊达比星

Also known as: Idarubicin HCl, 4-Demethoxydaunorubicin hydrochloride, Idamycin, 4-DMD HCl, (7S,9S)-9-acetyl-7-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-6,9,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride, Zavedos

Idarubicin hydrochloride (CAS 57852-57-0) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C26H28ClNO9 and a molecular weight of 533.955 g/mol. It is also known as Idarubicin HCl, 4-Demethoxydaunorubicin hydrochloride and Idamycin. Key properties include a melting point of 183-185ºC, a boiling point of 725.4ºC at 760 mmHg and a flash point of 392.5ºC. It is classified under GHS with signal word Danger and hazard statements H300, H351 — Suspected of causing cancer and H360 — May damage fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
57852-57-0
Jingsj CID
J-1960031-0
Molecular Formula
C26H28ClNO9
Chinese Name
盐酸伊达比星
Molecular Weight
533.955 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point183-185ºC
Boiling Point725.4ºC at 760 mmHg
Flash Point392.5ºC
Exact Mass533.145264
PSA176.61000
LogP2.52260
Storage Conditions-20℃

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger
  • H300
  • H351 — Suspected of causing cancer
  • H360 — May damage fertility or the unborn child

Activity & Biological Data

TargetTopoisomerase II
Additional Information[1]. Orlandi P, et al. Idarubicin and idarubicinol effects on breast cancer multicellular spheroids. J Chemother. 2005 Dec;17(6):663-7. [2]. Robert J. Clinical pharmacokinetics of idarubicin. Clin Pharmacokinet. 1993 Apr;24(4):275-88. [3]. Siegsmund MJ, et al. Enhanced in vitro cytotoxicity of idarubicin compared to epirubicin and doxorubicin in rat prostate carcinoma cells. Eur Urol. 1997;31(3):365-70. [4]. Gewirtz DA, et al. Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line. Cancer Chemother Pharmacol. 1998;41(5):361-

Frequently Asked Questions

What is the CAS number of Idarubicin hydrochloride?

The CAS number of Idarubicin hydrochloride is 57852-57-0.

What are the molecular formula and molecular weight of Idarubicin hydrochloride?

Idarubicin hydrochloride has molecular formula C26H28ClNO9 and molecular weight 533.955 g/mol.

Is Idarubicin hydrochloride hazardous?

Idarubicin hydrochloride has GHS signal word Danger and hazard statements H300; H351 — Suspected of causing cancer; H360 — May damage fertility or the unborn child.

What are the upstream and downstream products of Idarubicin hydrochloride?

For Idarubicin hydrochloride, Upstream Products: Daunorubicin hydrochloride, Idarubicinone.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Idarubicin hydrochloride (CAS 57852-57-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1960031-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.