Ibuprofen lysine

布洛芬赖氨酸盐

Also known as: Neoprofen, Ibuprofen Lysinate, L-Lysine mono[4-isobutyl-alpha-methylbenzeneacetate], Ibuprofen-lysine complex, Ibuprofen, L-lysine salt, MFCD01716155, 2-(4-Isobutylphenyl)propanoic acid - L-lysine (1:1)

Ibuprofen lysine (CAS 57469-77-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C19H30N2O3 and a molecular weight of 352.468 g/mol. It is also known as Neoprofen, Ibuprofen Lysinate and L-Lysine mono[4-isobutyl-alpha-methylbenzeneacetate]. Key property: a boiling point of 319.6ºC at 760 mmHg. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 57469-77-9
Jingsj CID: J-1415-1
Molecular Formula: C₁₉H₃₀N₂O₃
Chinese Name: 布洛芬赖氨酸盐
Molecular Weight: 352.468 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	319.6ºC at 760 mmHg
Exact Mass	352.236206
PSA	95.41000
LogP	3.91530
Storage Conditions	-20℃

Activity & Biological Data

Target	IC50: 13 μM (COX-1), 370 μM (COX-2)
Additional Information	[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. [3]. Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. [4]. Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7(1):8885. [5]. Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. [6]. Thomas Krøigård, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237(10):2645-2651. [7]. Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44(9):2237-45. [8]. M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92.

Target

IC50: 13 μM (COX-1), 370 μM (COX-2)

Additional Information

[1]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. [2]. Hassan Akrami, et al. Inhibitory effect of ibuprofen on tumor survival and angiogenesis in gastric cancer cell. Tumour Biol. 2015 May;36(5):3237-43. [3]. Sharon M Rymut, et al. Ibuprofen regulation of microtubule dynamics in cystic fibrosis epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L317-27. [4]. Emmanuelle Bignon, et al. Ibuprofen and ketoprofen potentiate UVA-induced cell death by a photosensitization process. Sci Rep. 2017 Aug 21;7(1):8885. [5]. Nathan D Pennock, et al. Ibuprofen supports macrophage differentiation, T cell recruitment, and tumor suppression in a model of postpartum breast cancer. J Immunother Cancer. 2018 Oct 1;6(1):98. [6]. Thomas Krøigård, et al. Protective effect of ibuprofen in a rat model of chronic oxaliplatin-induced peripheral neuropathy. Exp Brain Res. 2019 Oct;237(10):2645-2651. [7]. Sarah Ilkhanipour Rooney, et al. Ibuprofen Differentially Affects Supraspinatus Muscle and Tendon Adaptations to Exercise in a Rat Model. Am J Sports Med. 2016 Sep;44(9):2237-45. [8]. M W Konstan, et al. Ibuprofen attenuates the inflammatory response to Pseudomonas aeruginosa in a rat model of chronic pulmonary infection. Implications for antiinflammatory therapy in cystic fibrosis. Am Rev Respir Dis. 1990 Jan;141(1):186-92.

Frequently Asked Questions

What is the CAS number of Ibuprofen lysine?

The CAS number of Ibuprofen lysine is 57469-77-9.

What are the molecular formula and molecular weight of Ibuprofen lysine?

Ibuprofen lysine has molecular formula C19H30N2O3 and molecular weight 352.468 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ibuprofen lysine (CAS 57469-77-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1415-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.