Doxycycline

多西环素

Also known as: (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[Amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydro-1,3,12(2H,4H,5H)-tetracenetrione, 6-Deoxy-5-oxytetracycline, Doxinyl, Doxycen, Doxocycline, Doryx, Monodox, Ronaxan, Unidox, Vibramycin, azudoxat, doxitard, gs-3065, spanor

Doxycycline (CAS 564-25-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H24N2O8 and a molecular weight of 444.435 g/mol. It is also known as (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide, (2Z,4S,4aR,5S,5aR,6R,12aS)-2-[Amino(hydroxy)methylene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydro-1,3,12(2H,4H,5H)-tetracenetrione and 6-Deoxy-5-oxytetracycline. Key properties include a melting point of 206-209ºC, a boiling point of 685.2±55.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 368.2±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 564-25-0
Jingsj CID: J-2217-2
Molecular Formula: C₂₂H₂₄N₂O₈
Chinese Name: 多西环素
Molecular Weight: 444.435 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	206-209ºC
Boiling Point	685.2±55.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	368.2±31.5 °C
Exact Mass	444.153259
PSA	181.62000
LogP	1.36
Vapor Pressure	0.0±2.2 mmHg at 25°C
Refractive Index	1.737
Storage Conditions	2-8C

Activity & Biological Data

Additional Information	[1]. Briest W, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Luger AL, et al. Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems. Int J Mol Sci. 2018 May 17;19(5).

Additional Information

[1]. Briest W, et al. Doxycycline ameliorates the susceptibility to aortic lesions in a mouse model for the vascular type of Ehlers-Danlos syndrome. J Pharmacol Exp Ther. 2011 Jun;337(3):621-7. [2]. Luger AL, et al. Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems. Int J Mol Sci. 2018 May 17;19(5).

Customs & Trade Information

HS Code	3004909090

Frequently Asked Questions

What is the CAS number of Doxycycline?

The CAS number of Doxycycline is 564-25-0.

What are the molecular formula and molecular weight of Doxycycline?

Doxycycline has molecular formula C22H24N2O8 and molecular weight 444.435 g/mol.

What are the upstream and downstream products of Doxycycline?

For Doxycycline, Upstream Products: Metacycline hydrochloride, Doxycycline hydrochloride; Downstream Products: 4-Epidoxycycline, Doxycycline hydrochloride.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Doxycycline (CAS 564-25-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2217-2 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.