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Piperazin-2-one

Also known as: 2-Oxopiperazine, 2-Ketopiperazine, 3-Oxopiperazine, Piperazine-2-one, 2-Piperazinone, NSC 27441, PIPERAZIN-2-ONE, PIPERAZINONE

Piperazin-2-one (CAS 5625-67-2) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C4H8N2O and a molecular weight of 100.12 g/mol. Key properties include a melting point of 136-140 °C(lit.), a boiling point of 307.1±35.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 166.3±26.1 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H317 — May cause an allergic skin reaction and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
5625-67-2
Jingsj CID
J-4282-6
Molecular Formula
C4H8N2O
Molecular Weight
100.12 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point136-140 °C(lit.)
Boiling Point307.1±35.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point166.3±26.1 °C
Exact Mass100.063660
PSA41.13000
LogP-2.19
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.445

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H317 — May cause an allergic skin reaction
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933599090
Summary2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Piperazin-2-one?

The CAS number of Piperazin-2-one is 5625-67-2.

What are the molecular formula and molecular weight of Piperazin-2-one?

Piperazin-2-one has molecular formula C4H8N2O and molecular weight 100.12 g/mol.

Is Piperazin-2-one hazardous?

Piperazin-2-one has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Piperazin-2-one?

For Piperazin-2-one, Upstream Products: ethyl chloroacetate, Diethylamine, ethyl 2-[(2-aminoethyl)amino]acetate; Downstream Products: tert-Butyl 4-methyl-3-oxopiperazine-1-carboxylate, 4-Methylpiperazin-2-one, 1-(4-Fluorophenyl)piperazin-2-one.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Piperazin-2-one (CAS 5625-67-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-4282-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.