Nimustine hydrochloride

盐酸尼莫司汀

Also known as: ACNU, Nidran, Nimustine HCl, Nimustine monohydrochloride, 1-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3-nitrosourea hydrochloride, 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride, 3-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea hydrochloride (1:1), 4-Amino-5-({[N-(2-chloroethyl)-N-nitrosocarbamoyl]amino}methyl)-2-methylpyrimidin-1-ium chloride, N'-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride, MFCD01676942

Nimustine hydrochloride (CAS 55661-38-6) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H14Cl2N6O2 and a molecular weight of 309.152 g/mol. It is also known as ACNU, Nidran and Nimustine HCl. Key property: a melting point of 186 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 55661-38-6
Jingsj CID: J-36212-4
Molecular Formula: C₉H₁₄Cl₂N₆O₂
Chinese Name: 盐酸尼莫司汀
Molecular Weight: 309.152 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	186 °C
Exact Mass	308.055542
PSA	113.57000
LogP	2.57310

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Additional Information	[1]. Tomicic MT, et al. Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM. Oncotarget. 2015 Oct 20;6(32):33755-68. [2]. Kondo N, et al. FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ. PLoS One. 2011 May 9;6(5):e19659. [3]. Mineura K, et al. DNA lability induced by nimustine and ramustine in rat glioma cells. J Neurol Neurosurg Psychiatry. 1988 Nov;51(11):1391-4.

Additional Information

[1]. Tomicic MT, et al. Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM. Oncotarget. 2015 Oct 20;6(32):33755-68. [2]. Kondo N, et al. FANCD1/BRCA2 plays predominant role in the repair of DNA damage induced by ACNU or TMZ. PLoS One. 2011 May 9;6(5):e19659. [3]. Mineura K, et al. DNA lability induced by nimustine and ramustine in rat glioma cells. J Neurol Neurosurg Psychiatry. 1988 Nov;51(11):1391-4.

Frequently Asked Questions

What is the CAS number of Nimustine hydrochloride?

The CAS number of Nimustine hydrochloride is 55661-38-6.

What are the molecular formula and molecular weight of Nimustine hydrochloride?

Nimustine hydrochloride has molecular formula C9H14Cl2N6O2 and molecular weight 309.152 g/mol.

Is Nimustine hydrochloride hazardous?

Nimustine hydrochloride has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Nimustine hydrochloride (CAS 55661-38-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-36212-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.