Andrographolide
Also known as: Andrographolid, Andrographolide (standard), HMPL-004, 3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one
Andrographolide (CAS 5508-58-7) is a compound in the Esters category listed in the Jingsj chemical database. It has the molecular formula C20H30O5 and a molecular weight of 350.449 g/mol. Key properties include a melting point of 229-232ºC, a boiling point of 557.3±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 195.5±23.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 5508-58-7
- Jingsj CID
- J-18870-4
- Molecular Formula
- C20H30O5
- Molecular Weight
- 350.449 g/mol
- Category
- Esters
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 229-232ºC |
|---|---|
| Boiling Point | 557.3±50.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 195.5±23.6 °C |
| Exact Mass | 350.209320 |
| PSA | 86.99000 |
| LogP | 1.62 |
| Vapor Pressure | 0.0±3.4 mmHg at 25°C |
| Refractive Index | 1.568 |
Activity & Biological Data
| Target | p50 |
|---|---|
| Additional Information | [1]. Zhai ZJ, et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171(3):663-75. |
Customs & Trade Information
| HS Code | 29322980 |
|---|
Frequently Asked Questions
What is the CAS number of Andrographolide?
The CAS number of Andrographolide is 5508-58-7.
What are the molecular formula and molecular weight of Andrographolide?
Andrographolide has molecular formula C20H30O5 and molecular weight 350.449 g/mol.
What are the upstream and downstream products of Andrographolide?
For Andrographolide, Downstream Products: 1,2,5,6-Tetramethylnaphthalene.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Andrographolide (CAS 5508-58-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18870-4 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.