URB597

URB-597

Also known as: 3'-(aminocarbonyl)-1,1'-biphenyl-3-yl cyclohexylcarbamate, 3'-Carbamoyl-3-biphenylyl cyclohexylcarbamate, 3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate, 3'-Carbamoylbiphenyl-3-yl cyclohexylcarbamate, 3-(3-carbaMoylphenyl)phenyl N-cyclohexylcarbaMate, Carbamic acid, N-cyclohexyl-, 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester, Cyclohexyl-carbamic acid 3'-carbamoyl-biphenyl-3-yl ester, FAAH INHIBITOR II, FAAH inhibitor, KDS 4103 N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester, KDS-4103, N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester, N-Cyclohexylcarbamic acid 3'-(aminocarbonyl)[1,1'-biphenyl]-3-yl ester URB 597 KDS 4103, N-cyclohexylcarbamic acid [3-(3-carbamoylphenyl)phenyl] ester, URB 597 NEW, [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate, cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester

URB597 (CAS 546141-08-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H22N2O3 and a molecular weight of 338.400 g/mol. It is also known as 3'-(aminocarbonyl)-1,1'-biphenyl-3-yl cyclohexylcarbamate, 3'-Carbamoyl-3-biphenylyl cyclohexylcarbamate and 3'-Carbamoyl-[1,1'-biphenyl]-3-yl cyclohexylcarbamate. Key properties include a boiling point of 533.2±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 276.3±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H319 — Causes serious eye irritation and H410 — Very toxic to aquatic life with long lasting effects. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 546141-08-6
Jingsj CID: J-1970543-9
Molecular Formula: C₂₀H₂₂N₂O₃
Chinese Name: URB-597
Molecular Weight: 338.400 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	533.2±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	276.3±30.1 °C
Exact Mass	338.163055
PSA	81.42000
LogP	3.51
Appearance	powder \| white
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.618
Storage Conditions	2-8°C
Additional Property	DMSO: ~14 mg/mL, soluble

GHS Safety & Compliance

Irritant / Environmental HazardSignal word: Warning

H319 — Causes serious eye irritation
H410 — Very toxic to aquatic life with long lasting effects

Activity & Biological Data

Additional Information	[1]. Mor M, et al. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. J Med Chem, 2004, 47(21), 4998-5008. [2]. Tham CS, et al. Inhibition of microglial fatty acid amide hydrolase modulates LPS stimulated release of inflammatory mediators. FEBS Lett, 2007, 581(16), 2899-2904. [3]. Fegley D, et al. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther. 2005 Apr;313(1):352-8. [4]. Jayamanne A, et al. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol, 2006, 147(3), 281-288.

Additional Information

[1]. Mor M, et al. Cyclohexylcarbamic acid 3'- or 4'-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure-activity relationships, and molecular modeling studies. J Med Chem, 2004, 47(21), 4998-5008. [2]. Tham CS, et al. Inhibition of microglial fatty acid amide hydrolase modulates LPS stimulated release of inflammatory mediators. FEBS Lett, 2007, 581(16), 2899-2904. [3]. Fegley D, et al. Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation. J Pharmacol Exp Ther. 2005 Apr;313(1):352-8. [4]. Jayamanne A, et al. Actions of the FAAH inhibitor URB597 in neuropathic and inflammatory chronic pain models. Br J Pharmacol, 2006, 147(3), 281-288.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of URB597?

The CAS number of URB597 is 546141-08-6.

What are the molecular formula and molecular weight of URB597?

URB597 has molecular formula C20H22N2O3 and molecular weight 338.400 g/mol.

Is URB597 hazardous?

URB597 has GHS signal word Warning and hazard statements H319 — Causes serious eye irritation; H410 — Very toxic to aquatic life with long lasting effects.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "URB597 (CAS 546141-08-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1970543-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.