Isoniazid
Also known as: Isonicotinic acid hydrazide, INH, 4-pyridinecarbohydrazide, pyridine-4-carbohydrazide, isonicotinohydrazide, isonicotinyl hydrazide, Nydrazid, Rimifon, Hyzyd, Laniazid, HIA
Isoniazid (CAS 54-85-3) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H7N3O and a molecular weight of 137.139 g/mol. Key properties include a melting point of 171-173 °C(lit.), a density of 1.2±0.1 g/cm3 and a flash point of >250°C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H315 — Causes skin irritation. It is listed by 2 suppliers, 1 of which publish reference prices, from 0.24 to 0.24 CNY per 500g. Record last updated Nov 3, 2026.
- CAS No.
- 54-85-3
- Jingsj CID
- J-806614-5
- Molecular Formula
- C6H7N3O
- Molecular Weight
- 137.139 g/mol
- Category
- Organic Bases
- Last updated
- 11/3/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | 98% 500g | ¥120.00 | $0.04 /gBest ¥0.24/g CNY | CN China MOQ 标准 | |
Made to Order | 98% 5g | - | - | CN China MOQ 5g | |
Made to Order | 98% 25g | - | - | CN China MOQ 25g |
Physicochemical Properties
| Melting Point | 171-173 °C(lit.) |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | >250°C |
| Exact Mass | 137.058914 |
| PSA | 68.01000 |
| LogP | -0.89 |
| Refractive Index | 1.584 |
| Stability | Stability Stable, but may be air or light sensitive. Combustible. Incompatible with strong oxidizing agents, chloral, aldehydes, iodine, ferric salts, hypochlorites. |
| Additional Property | 14 g/100 mL (25 ºC) |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H315 — Causes skin irritation
Activity & Biological Data
| Additional Information | [1]. Suarez, J., et al., An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG). J Biol Chem, 2009. 284(11): p. 7017-29. [2]. Timmins, G.S., et al., Nitric oxide generated from isoniazid activation by KatG: source of nitric oxide and activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother, 2004. 48(8): p. 3006-9. [3]. Singh, R., et al., PA-824 kills nonreplicating Mycobacterium tuberculosis by intracellular NO release. Science, 2008. 322(5906): p. 1392-5. [4]. Ahmad, Z., et al., Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig. J Infect Dis, 2009. 200(7): p. 1136-43. |
|---|
Customs & Trade Information
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Isoniazid?
The CAS number of Isoniazid is 54-85-3.
What are the molecular formula and molecular weight of Isoniazid?
Isoniazid has molecular formula C6H7N3O and molecular weight 137.139 g/mol.
Which suppliers offer Isoniazid?
2 supplier(s) listed; reference unit price ¥0.24–0.24 /g.
Is Isoniazid hazardous?
Isoniazid has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation.
What are the upstream and downstream products of Isoniazid?
For Isoniazid, Upstream Products: Isonicotinamide, Methyl isonicotinate, Ethyl isonicotinate; Downstream Products: 3,6-Di(4-pyridyl)-1,2,4,5-tetrazine, 4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol, Piperidine-4-carboxamide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Isoniazid (CAS 54-85-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-806614-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.