1-Hydroxyibuprofen
1-羟基异丁基苯基-1'-甲基丙酸
Also known as: 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic acid, 1-Hydroxy Ibuprofen, 1-OH-ibuprofen, Ibuprofen Impurity L, UNII-8A1S87ZA87, Ibuprofen Impurity 12
1-Hydroxyibuprofen (CAS 53949-53-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C13H18O3 and a molecular weight of 222.28000 g/mol. It is also known as 2-[4-(1-Hydroxy-2-methylpropyl)phenyl]propanoic acid, 1-Hydroxy Ibuprofen and 1-OH-ibuprofen. Key property: a melting point of 80-85ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 53949-53-4
- Jingsj CID
- J-1959385-0
- Molecular Formula
- C13H18O3
- Chinese Name
- 1-羟基异丁基苯基-1'-甲基丙酸
- Molecular Weight
- 222.28000 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 80-85ºC |
|---|---|
| Exact Mass | 222.12600 |
| PSA | 57.53000 |
| LogP | 2.56410 |
| Storage Conditions | -20°C Freezer |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Additional Information | [1]. Yujie He, et al. Metabolism of Ibuprofen by Phragmites australis: Uptake and Phytodegradation. Environ Sci Technol. 2017 Apr 18;51(8):4576-4584. [2]. Noreen Y, et al. Development of a radiochemical cyclooxygenase-1 and -2 in vitro assay for identification of natural products as inhibitors of prostaglandin biosynthesis. J Nat Prod. 1998 Jan;61(1):2-7. |
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Frequently Asked Questions
What is the CAS number of 1-Hydroxyibuprofen?
The CAS number of 1-Hydroxyibuprofen is 53949-53-4.
What are the molecular formula and molecular weight of 1-Hydroxyibuprofen?
1-Hydroxyibuprofen has molecular formula C13H18O3 and molecular weight 222.28000 g/mol.
Is 1-Hydroxyibuprofen hazardous?
1-Hydroxyibuprofen has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of 1-Hydroxyibuprofen?
For 1-Hydroxyibuprofen, Upstream Products: Ibuprofen.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "1-Hydroxyibuprofen (CAS 53949-53-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1959385-0 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.