Pirfenidone
Also known as: 5-Methyl-1-phenyl-2(1H)-pyridinone, 5-Methyl-1-phenylpyridin-2(1H)-one, AMR-69, S-7701, Esbriet, Pirespa, 5-Methyl-1-phenylpyridine-2(1H)-one, 5-methyl-1-phenyl-2-pyridone, MFCD00866047
Pirfenidone (CAS 53179-13-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C12H11NO and a molecular weight of 185.222 g/mol. Key properties include a melting point of 96-97ºC, a boiling point of 329.1±15.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 152.7±11.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 53179-13-8
- Jingsj CID
- J-1326986-8
- Molecular Formula
- C12H11NO
- Molecular Weight
- 185.222 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 96-97ºC |
|---|---|
| Boiling Point | 329.1±15.0 °C at 760 mmHg |
| Density | 1.1±0.1 g/cm3 |
| Flash Point | 152.7±11.6 °C |
| Exact Mass | 185.084061 |
| PSA | 22.00000 |
| LogP | 1.82 |
| Appearance | solid |
| Vapor Pressure | 0.0±0.7 mmHg at 25°C |
| Refractive Index | 1.592 |
| Storage Conditions | Store at RT |
| Additional Property | DMSO: ≥10 mg/mL, soluble |
GHS Safety & Compliance
- H302 — Harmful if swallowed
Activity & Biological Data
| Target | TGF-β2[1] |
|---|---|
| Additional Information | [1]. Burghardt I, et al. Pirfenidone inhibits TGF-beta expression in malignant glioma cells. Biochem Biophys Res Commun. 2007 Mar 9;354(2):542-7. [2]. Nakazato H, et al. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level. Eur J Pharmacol. 2002 Jun 20;446(1-3):177-85. [3]. Yang Y, et al. Inhibition of Pirfenidone on TGF-beta2 induced proliferation, migration and epithlial-mesenchymal transitionof human lens epithelial cells line SRA01/04. PLoS One. 2013;8(2):e56837. [4]. Inomata M, et al. Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis. Respir Res. 2014 Feb 8;15:16. [5]. Brooks D, et al. Limited fibrosis accompanies triple-negative breast cancer metastasis in multiple model systems and is not a preventive target. Oncotarget. 2018 May 4;9(34):23462-23481. |
Customs & Trade Information
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Pirfenidone?
The CAS number of Pirfenidone is 53179-13-8.
What are the molecular formula and molecular weight of Pirfenidone?
Pirfenidone has molecular formula C12H11NO and molecular weight 185.222 g/mol.
Is Pirfenidone hazardous?
Pirfenidone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.
What are the upstream and downstream products of Pirfenidone?
For Pirfenidone, Upstream Products: 5-Methyl-2(1H)-pyridinone, Iodobenzene, Bromobenzene.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Pirfenidone (CAS 53179-13-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1326986-8 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.