(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸

Also known as: (R)-Trolox, Trolox (R)-Isomer, (2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid, UNII-1O8B70QB9P, MFCD00180755

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (CAS 53101-49-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C14H18O4 and a molecular weight of 250.29000 g/mol. It is also known as (R)-Trolox, Trolox (R)-Isomer and (2R)-6-Hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid. Key properties include a melting point of 162ºC (dec.)(lit.), a boiling point of 450.3ºC at 760 mmHg, a density of 1.219g/cm3 and a flash point of 171ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
53101-49-8
Jingsj CID
J-1008237-1
Molecular Formula
C14H18O4
Chinese Name
(R)-(+)-6-羟基-2,5,7,8-四甲基色满-2-羧酸
Molecular Weight
250.29000 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point162ºC (dec.)(lit.)
Boiling Point450.3ºC at 760 mmHg
Density1.219g/cm3
Flash Point171ºC
Exact Mass250.12100
PSA66.76000
LogP2.48570
Refractive Index1.567

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Yu L. Inhibitory effects of (S)- and (R)-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acids on tyrosinase activity. J Agric Food Chem. 2003 Apr 9;51(8):2344-7.

Customs & Trade Information

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid?

The CAS number of (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid is 53101-49-8.

What are the molecular formula and molecular weight of (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid?

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has molecular formula C14H18O4 and molecular weight 250.29000 g/mol.

Is (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid hazardous?

(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid?

For (R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid, Upstream Products: 2,5-dimethoxy-3,4,6-trimethylbenzaldehyde.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "(R)-(+)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (CAS 53101-49-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1008237-1 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.