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Isosorbide dimethyl ether

Also known as: 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol, 1,4:3,6-Dianhydro-D-glucitol dimethyl ether, Dimethyl isosorbide, O,O-Dimethylisosorbide, (3R,3aR,6S,6aR)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan, (3R,6S)-3,6-Dimethoxyhexahydrofuro[3,2-b]furan, D-Glucitol, 1,4:3,6-dianhydro-2,5-di-O-methyl-

Isosorbide dimethyl ether (CAS 5306-85-4) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C8H14O4 and a molecular weight of 174.19 g/mol. Key properties include a melting point of -70°C, a boiling point of 236.4±40.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 108.3±0.0 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
5306-85-4
Jingsj CID
J-45288-7
Molecular Formula
C8H14O4
Molecular Weight
174.19 g/mol
Category
Alcohols
Last updated
8/21/2026

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Physicochemical Properties

Melting Point-70°C
Boiling Point236.4±40.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point108.3±0.0 °C
Exact Mass174.089203
PSA36.92000
LogP-0.65
Vapor Pressure0.1±0.5 mmHg at 25°C
Refractive Index1.466

Activity & Biological Data

Additional Information[1]. Russo F, et al. Dimethyl isosorbide as a green solvent for sustainable ultrafiltration and microfiltration membrane preparation[J]. ACS Sustainable Chemistry & Engineering, 2019, 8(1): 659-668. [2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Customs & Trade Information

HS Code2932999099
Summary2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Isosorbide dimethyl ether?

The CAS number of Isosorbide dimethyl ether is 5306-85-4.

What are the molecular formula and molecular weight of Isosorbide dimethyl ether?

Isosorbide dimethyl ether has molecular formula C8H14O4 and molecular weight 174.19 g/mol.

What are the upstream and downstream products of Isosorbide dimethyl ether?

For Isosorbide dimethyl ether, Upstream Products: Dimethyl Carbonate, Isosorbide, Sorbitol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Isosorbide dimethyl ether (CAS 5306-85-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45288-7 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.