Tetrahydrocortisol

四氢皮质醇

Also known as: Urocortisol, 3α,11β,17α,21-Tetrahydroxy-5β-pregnan-20-one, 5β-Tetrahydrocortisol, Tetrahydro F, Tetrahydrocompound F, Tetrahydrohydrocortisone, Ba 2682

Tetrahydrocortisol (CAS 53-02-1) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C21H34O5 and a molecular weight of 366.49200 g/mol. It is also known as Urocortisol, 3α,11β,17α,21-Tetrahydroxy-5β-pregnan-20-one and 5β-Tetrahydrocortisol. Key properties include a melting point of -108ºC(lit.), a boiling point of 65-67ºC(lit.), a density of 1.253g/cm3 and a flash point of 297.6ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 53-02-1
Jingsj CID: J-1974902-2
Molecular Formula: C₂₁H₃₄O₅
Chinese Name: 四氢皮质醇
Molecular Weight: 366.49200 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	-108ºC(lit.)
Boiling Point	65-67ºC(lit.)
Density	1.253g/cm3
Flash Point	297.6ºC
Exact Mass	366.24100
PSA	97.99000
LogP	1.65330
Refractive Index	n20/D 1.407(lit.)
Storage Conditions	-20°C

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Webster SP, et al. Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™). Br J Pharmacol. 2017 Mar;174(5):396-408. [2]. Turpeinen U, et al. Determination of free tetrahydrocortisol and tetrahydrocortisone ratio in urine by liquid chromatography-tandem mass spectrometry. Scand J Clin Lab Invest. 2006;66(2):147-59.

Target

Human Endogenous Metabolite

Additional Information

[1]. Webster SP, et al. Selection and early clinical evaluation of the brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor UE2343 (Xanamem™). Br J Pharmacol. 2017 Mar;174(5):396-408. [2]. Turpeinen U, et al. Determination of free tetrahydrocortisol and tetrahydrocortisone ratio in urine by liquid chromatography-tandem mass spectrometry. Scand J Clin Lab Invest. 2006;66(2):147-59.

Frequently Asked Questions

What is the CAS number of Tetrahydrocortisol?

The CAS number of Tetrahydrocortisol is 53-02-1.

What are the molecular formula and molecular weight of Tetrahydrocortisol?

Tetrahydrocortisol has molecular formula C21H34O5 and molecular weight 366.49200 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tetrahydrocortisol (CAS 53-02-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974902-2 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.