Ginsenoside Rd

人参皂苷Rd

Also known as: Gypenoside VIII, Chikusetsusaponin FK7, Sanchinoside Rd, Panaxoside Rd, (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-

Ginsenoside Rd (CAS 52705-93-8) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C48H82O18 and a molecular weight of 947.154 g/mol. It is also known as Gypenoside VIII, Chikusetsusaponin FK7 and Sanchinoside Rd. Key properties include a melting point of 207 °C(dec.), a boiling point of 1015.6±65.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 568.0±34.3 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
52705-93-8
Jingsj CID
J-29805-4
Molecular Formula
C48H82O18
Chinese Name
人参皂苷Rd
Molecular Weight
947.154 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point207 °C(dec.)
Boiling Point1015.6±65.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point568.0±34.3 °C
Exact Mass946.550110
PSA298.14000
LogP3.24
Vapor Pressure0.0±0.6 mmHg at 25°C
Refractive Index1.611
Storage Conditions2-8°C

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

TargetNF-κB:12.05 μM (IC50, in HepG2 cells) COX-2 L-type calcium channel CYP2D6:58 μM (IC50) CYP1A2:78.4 μM (IC50) CYP3A4:81.7 μM (IC50) CYP2C9:85.1 μM (IC50)
Additional Information[1]. Song SB, et al. Inhibition of TNF-α-mediated NF-κB Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves. J Ginseng Res. 2012 Apr;36(2):146-52. [2]. Lu C, et al. Inhibition of L-type Ca 2+ current by ginsenoside Rd in rat ventricular myocytes. J Ginseng Res. 2015 Apr;39(2):169-77. [3]. Huang G, et al. Ginsenosides Rb3 and Rd reduce polyps formation while reinstate the dysbiotic gut microbiota and the intestinal microenvironment in Apc Min/+ mice. Sci Rep. 2017 Oct 2;7(1):12552. [4]. Liu Y, et al. Ginsenoside metabolites, rather than naturally occurring ginsenosides, lead to inhibition of human cytochrome P450 enzymes. Toxicol Sci. 2006 Jun;91(2):356-64.

Frequently Asked Questions

What is the CAS number of Ginsenoside Rd?

The CAS number of Ginsenoside Rd is 52705-93-8.

What are the molecular formula and molecular weight of Ginsenoside Rd?

Ginsenoside Rd has molecular formula C48H82O18 and molecular weight 947.154 g/mol.

Is Ginsenoside Rd hazardous?

Ginsenoside Rd has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ginsenoside Rd (CAS 52705-93-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-29805-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.