Xylometazoline

赛洛唑啉

Also known as: Otrivine, Otrivin, Otriven, Novorin, Xylomethazoline, UNII-WPY40FTH8K, Xilometazolina, Xylometazolinum, 2-(4-tert-butyl-2,6-dimethylbenzyl)-4,5-dihydro-1H-imidazole, 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole

Xylometazoline (CAS 526-36-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H24N2 and a molecular weight of 244.38 g/mol. It is also known as Otrivine, Otrivin and Otriven. Key properties include a boiling point of 394.2ºC at 760mmHg, a density of 1g/cm3 and a flash point of 192.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
526-36-3
Jingsj CID
J-1958777-4
Molecular Formula
C16H24N2
Chinese Name
赛洛唑啉
Molecular Weight
244.38 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point394.2ºC at 760mmHg
Density1g/cm3
Flash Point192.2ºC
Exact Mass244.19400
PSA24.39000
LogP2.90950
Storage Conditions-20°C

Activity & Biological Data

TargetAlpha-1A adrenergic receptor:0.05 μM (Ki) Alpha-1B adrenergic receptor:0.30 μM (Ki) Alpha-1D adrenergic receptor:0.15 μM (Ki) Alpha-2A adrenergic receptor:0.88 μM (Ki) Alpha-2B adrenergic receptor:1.7 μM (Ki) Alpha-2C adrenergic receptor:0.19 μM (Ki)
Additional Information[1]. Ronald Eccles, et al. The nasal decongestant effect of xylometazoline in the common cold. Am J Rhinol. 2008 Sep-Oct;22(5):491-6. [2]. Britta Haenisch, et al. Alpha-adrenoceptor agonistic activity of oxymetazoline and xylometazoline. Fundam Clin Pharmacol. 2010 Dec;24(6):729-39.

Customs & Trade Information

HS Code2933290090
Summary2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Xylometazoline?

The CAS number of Xylometazoline is 526-36-3.

What are the molecular formula and molecular weight of Xylometazoline?

Xylometazoline has molecular formula C16H24N2 and molecular weight 244.38 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Xylometazoline (CAS 526-36-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958777-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.