Physcion
Also known as: 1,8-dihydroxy-3-methoxy-6-methylanthraquinone, Emodin-3-methyl ether, Parietin, Rheochrysidin, Physcione, Methylemodin, 1,8-dihydroxy-3-methoxy-6-methylanthracene-9,10-dione, Physcic acid, 6-O-Methylemodin, Emodin monomethyl ether
Physcion (CAS 521-61-9) is a compound in the Ethers category listed in the Jingsj chemical database. It has the molecular formula C16H12O5 and a molecular weight of 284.26 g/mol. Key properties include a melting point of 196-206°C, a boiling point of 560.5±50.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 215.4±23.6 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 521-61-9
- Jingsj CID
- J-5479-5
- Molecular Formula
- C16H12O5
- Molecular Weight
- 284.26 g/mol
- Category
- Ethers
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 196-206°C |
|---|---|
| Boiling Point | 560.5±50.0 °C at 760 mmHg |
| Density | 1.4±0.1 g/cm3 |
| Flash Point | 215.4±23.6 °C |
| Exact Mass | 284.068481 |
| PSA | 83.83000 |
| LogP | 5.20 |
| Vapor Pressure | 0.0±1.6 mmHg at 25°C |
| Refractive Index | 1.678 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | IC50: 38.5 μM (6-phosphogluconate dehydrogenase)[1] Kd: 26.0 μM (6-phosphogluconate dehydrogenase)[1] |
|---|---|
| Additional Information | [1]. Lin R, et al. 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov;17(11):1484-96. [2]. Pang MJ, et al. Physcion, a naturally occurring anthraquinone derivative, induces apoptosis and autophagy in human nasopharyngeal carcinoma. Acta Pharmacol Sin. 2016 Dec;37(12):1623-1640. |
Customs & Trade Information
| HS Code | 2914690090 |
|---|---|
| Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Physcion?
The CAS number of Physcion is 521-61-9.
What are the molecular formula and molecular weight of Physcion?
Physcion has molecular formula C16H12O5 and molecular weight 284.26 g/mol.
Is Physcion hazardous?
Physcion has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Physcion?
For Physcion, Upstream Products: Emodin, Dimethyl sulfate, iodomethane; Downstream Products: 2-METHYLANTHRACENE, Emodin, iodomethane.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Physcion (CAS 521-61-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-5479-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.