Aldosterone
Also known as: 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al, 11β,21-Dihydroxypregn-4-ene-3,18,20-trione, 18-Oxocorticosterone, Aldocorten, Aldocortine, Aldocortin, Electrocortin, Lektrocortin, Reichstein X
Aldosterone (CAS 52-39-1) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C21H28O5 and a molecular weight of 360.444 g/mol. Key properties include a melting point of 170-172ºC, a boiling point of 568.1±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 311.4±26.6 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H302 — Harmful if swallowed and H312 — Harmful in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 52-39-1
- Jingsj CID
- J-31657-2
- Molecular Formula
- C21H28O5
- Molecular Weight
- 360.444 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 170-172ºC |
|---|---|
| Boiling Point | 568.1±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 311.4±26.6 °C |
| Exact Mass | 360.193665 |
| PSA | 91.67000 |
| LogP | 0.73 |
| Vapor Pressure | 0.0±3.5 mmHg at 25°C |
| Refractive Index | 1.586 |
GHS Safety & Compliance
- H225 — Highly flammable liquid and vapour
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H332 — Harmful if inhaled
- H319 — Causes serious eye irritation
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Nanba K, et al. Aging and Adrenal Aldosterone Production. Hypertension. 2018 Feb;71(2):218-223. [2]. Cannavo A, et al. Aldosterone and Mineralocorticoid Receptor System in Cardiovascular Physiology and Pathophysiology. Oxid Med Cell Longev. 2018 Sep 19;2018:1204598. [3]. Ikeda U, et al. Aldosterone inhibits nitric oxide synthesis in rat vascular smooth muscle cells induced by interleukin-1 beta. Eur J Pharmacol. 1995 Jul 18;290(2):69-73. [4]. Martín-Fernández B, et al. Beneficial effects of proanthocyanidins in the cardiac alterations induced by aldosterone in ratheart through mineralocorticoid receptor blockade. PLoS One. 2014 Oct 29;9(10):e111104. [5]. Dinh QN, et al. Aldosterone-induced oxidative stress and inflammation in the brain are mediated by the endothelial cell mineralocorticoid receptor. Brain Res. 2016 Apr 15;1637:146-153. |
Customs & Trade Information
| HS Code | 29372900 |
|---|
Frequently Asked Questions
What is the CAS number of Aldosterone?
The CAS number of Aldosterone is 52-39-1.
What are the molecular formula and molecular weight of Aldosterone?
Aldosterone has molecular formula C21H28O5 and molecular weight 360.444 g/mol.
Is Aldosterone hazardous?
Aldosterone has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H302 — Harmful if swallowed; H312 — Harmful in contact with skin.
What are the upstream and downstream products of Aldosterone?
For Aldosterone, Upstream Products: Pregn-4-en-18-al, 21-(acetyloxy)-11-hydroxy-3,20-dioxo-, (11β)-, Pregnenolone; Downstream Products: 1-Dehydroaldosterone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Aldosterone (CAS 52-39-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-31657-2 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.