4-Methylaminoantipyrine

4-(甲氨基)安替比林

Also known as: 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one, 4-Monomethylaminoantipyrine, Noraminopyrine, Noramidopyrine, Methylaminoantipyrine, N-Methylaminophenazone, 4-Methylaminophenazone, 1-phenyl-2,3-dimethyl-4-methylamino-5-pyrazolone, 2,3-Dimethyl-4-methylamino-1-phenyl-3-pyrazolin-5-one, 4-(Methylamino)-antipyrine, 4-(N-methyl)-aminoantipyrine, Monomethylaminoantipyrine

4-Methylaminoantipyrine (CAS 519-98-2) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H15N3O and a molecular weight of 217.267 g/mol. It is also known as 1,2-dihydro-1,5-dimethyl-4-(methylamino)-2-phenyl-3H-pyrazol-3-one, 4-Monomethylaminoantipyrine and Noraminopyrine. Key properties include a melting point of 50-53ºC, a boiling point of 324.5±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 150.0±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 519-98-2
Jingsj CID: J-1981975-0
Molecular Formula: C₁₂H₁₅N₃O
Chinese Name: 4-(甲氨基)安替比林
Molecular Weight: 217.267 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	50-53ºC
Boiling Point	324.5±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	150.0±28.7 °C
Exact Mass	217.121506
PSA	38.96000
LogP	0.02
Vapor Pressure	0.0±0.7 mmHg at 25°C
Refractive Index	1.619
Storage Conditions	-20℃

Activity & Biological Data

Target	COX[2][3]
Additional Information	[1]. Burmańczuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec;39(6):616-620. [2]. Campos C1, et al. Regulation of cyclooxygenase activity by metamizol. Eur J Pharmacol. 1999 Aug 13;378(3):339-47. [3]. Ariza A, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016 Mar 31;6:23845.

Target

COX[2][3]

Additional Information

[1]. Burmańczuk A, et al. Pharmacokinetic investigations of the marker active metabolites 4-methylamino-antipyrine and 4-amino-antipyrine after intramuscular injection of metamizole in healthy piglets. J Vet Pharmacol Ther. 2016 Dec;39(6):616-620. [2]. Campos C1, et al. Regulation of cyclooxygenase activity by metamizol. Eur J Pharmacol. 1999 Aug 13;378(3):339-47. [3]. Ariza A, et al. Pyrazolones metabolites are relevant for identifying selective anaphylaxis to metamizole. Sci Rep. 2016 Mar 31;6:23845.

Customs & Trade Information

HS Code	2933199090
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 4-Methylaminoantipyrine?

The CAS number of 4-Methylaminoantipyrine is 519-98-2.

What are the molecular formula and molecular weight of 4-Methylaminoantipyrine?

4-Methylaminoantipyrine has molecular formula C12H15N3O and molecular weight 217.267 g/mol.

What are the upstream and downstream products of 4-Methylaminoantipyrine?

For 4-Methylaminoantipyrine, Upstream Products: Metamizole sodium, Morphine sulfate, 4-Acetamidoantipyrine; Downstream Products: Aminopyrine, Metamizole sodium monohydrate.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "4-Methylaminoantipyrine (CAS 519-98-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1981975-0 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.