Pizotifen malate

苯噻啶苹果酸盐

Also known as: Pizotyline malate, Pizotifen hydrogen malate, Sandomigran, Mosegor, Sanomtgran, BC-105, Litec malate, malic acid, compound with 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine (1:1)

Pizotifen malate (CAS 5189-11-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C23H27NO5S and a molecular weight of 429.53 g/mol. It is also known as Pizotyline malate, Pizotifen hydrogen malate and Sandomigran. Key properties include a melting point of 185-186° (dec), a boiling point of 436.7ºC at 760 mmHg and a flash point of 217.9ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 5189-11-7
Jingsj CID: J-1979990-4
Molecular Formula: C₂₃H₂₇NO₅S
Chinese Name: 苯噻啶苹果酸盐
Molecular Weight: 429.53 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	185-186° (dec)
Boiling Point	436.7ºC at 760 mmHg
Flash Point	217.9ºC
PSA	106.08000
LogP	4.02390
Storage Conditions	2–8 °C

Activity & Biological Data

Target	5-HT2A Receptor 5-HT1C Receptor
Additional Information	[1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52. [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026. [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.

Target

5-HT2A Receptor 5-HT1C Receptor

Additional Information

[1]. Mylecharane EJ, et al. 5-HT2 receptor antagonists and migraine therapy. J Neurol. 1991;238 Suppl 1:S45-52. [2]. Lin OA, et al. The antidepressant 5-HT2A receptor antagonists pizotifen and cyproheptadine inhibit serotonin-enhanced platelet function. PLoS One. 2014 Jan 23;9(1):e87026. [3]. Ujházy E, et al. Teratological and cytogenetical evaluation of two antihistamines (pipethiadene and pizotifen maleate) in mice. Agents Actions. 1988 Apr;23(3-4):376-8.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Pizotifen malate?

The CAS number of Pizotifen malate is 5189-11-7.

What are the molecular formula and molecular weight of Pizotifen malate?

Pizotifen malate has molecular formula C23H27NO5S and molecular weight 429.53 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Pizotifen malate (CAS 5189-11-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1979990-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.