Tarenflurbil

(R)-氟比洛芬

Also known as: (R)-Flurbiprofen, R-Flurbiprofen, R-(-)-Flurbiprofen, (-)-Flurbiprofen, (2R)-2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid, (2R)-2-(2-Fluorobiphenyl-4-yl)propanoic acid, (2R)-2-(3-Fluoro-4-phenylphenyl)propanoic acid, (R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid, (R)-(−)-2-Fluoro-α-methyl-4-biphenylacetic acid, (R)-2-Flurbiprofen, Flurizan, MPC-7869, E-7869, UNII-501W00OOWA, MFCD00869714

Tarenflurbil (CAS 51543-40-9) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H13FO2 and a molecular weight of 244.261 g/mol. It is also known as (R)-Flurbiprofen, R-Flurbiprofen and R-(-)-Flurbiprofen. Key properties include a melting point of 110-113ºC, a boiling point of 376.2±30.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 181.3±24.6 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 51543-40-9
Jingsj CID: J-25813-9
Molecular Formula: C₁₅H₁₃FO₂
Chinese Name: (R)-氟比洛芬
Molecular Weight: 244.261 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	110-113ºC
Boiling Point	376.2±30.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	181.3±24.6 °C
Exact Mass	244.089951
PSA	37.30000
LogP	4.11
Appearance	Crystalline Powder \| White to off-white
Vapor Pressure	0.0±0.9 mmHg at 25°C
Refractive Index	1.568

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Target	IC50: 75 μM (RXRα)[1]
Additional Information	[1]. You X, et al. Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid. J Neurochem. 2009 Oct;111(1):142-9. [2]. Wanngren J, et al. Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. J Biol Chem. 2012 Sep 21;287(39):32640-50. [3]. Schmitz K, et al. R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice. EMBO Mol Med. 2014 Sep 30;6(11):1398-422.

Target

IC50: 75 μM (RXRα)[1]

Additional Information

[1]. You X, et al. Retinoid X receptor-alpha mediates (R )-flurbiprofen's effect on the levels of Alzheimer's beta-amyloid. J Neurochem. 2009 Oct;111(1):142-9. [2]. Wanngren J, et al. Second generation γ-secretase modulators exhibit different modulation of Notch β and Aβ production. J Biol Chem. 2012 Sep 21;287(39):32640-50. [3]. Schmitz K, et al. R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice. EMBO Mol Med. 2014 Sep 30;6(11):1398-422.

Customs & Trade Information

HS Code	2916399090
Summary	2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Tarenflurbil?

The CAS number of Tarenflurbil is 51543-40-9.

What are the molecular formula and molecular weight of Tarenflurbil?

Tarenflurbil has molecular formula C15H13FO2 and molecular weight 244.261 g/mol.

Is Tarenflurbil hazardous?

Tarenflurbil has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Tarenflurbil (CAS 51543-40-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25813-9 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.