Nω-Nitro-L-arginine methyl ester hydrochloride
Also known as: L-NAME hydrochloride, NG-Nitro-L-arginine-methyl ester hydrochloride, H-Arg(NO2)-OMe·HCl, N'-Nitro-L-arginine-methyl ester hydrochloride, Nω-Nitro-L-arginine methyl ester hydrochloride, N-Nitro-L-arginine methyl ester hydrochloride, L-NG-Nitroarginine Methyl Ester hydrochloride
Nω-Nitro-L-arginine methyl ester hydrochloride (CAS 51298-62-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C7H16ClN5O4 and a molecular weight of 269.69 g/mol. Key properties include a melting point of 157-161 °C (dec.), a boiling point of 383.5ºC at 760 mmHg and a flash point of 185.8ºC. It is listed by 1 supplier, from 7.04 to 8.40 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 51298-62-5
- Jingsj CID
- J-48832-5
- Molecular Formula
- C7H16ClN5O4
- Molecular Weight
- 269.69 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
Made to Order | 97% 500g | ¥3,520.00 | $1.05 /gBest ¥7.04/g CNY | CN China MOQ 500g | |
Made to Order | 97% 100g | ¥820.00 | $1.23 /g ¥8.20/g CNY | CN China MOQ 100g | |
Made to Order | 97% 25g | ¥210.00 | $1.26 /g ¥8.40/g CNY | CN China MOQ 25g |
Physicochemical Properties
| Melting Point | 157-161 °C (dec.) |
|---|---|
| Boiling Point | 383.5ºC at 760 mmHg |
| Flash Point | 185.8ºC |
| Exact Mass | 269.089081 |
| PSA | 146.05000 |
| LogP | 1.47960 |
| Refractive Index | 15 ° (C=3, MeOH) |
| SMILES | COC(=O)[C@H](CCCN=C(N)N[N+](=O)[O-])N.Cl |
| InChIKey | QBNXAGZYLSRPJK-JEDNCBNOSA-N |
| InChI | 1S/C7H15N5O4.ClH/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15;/h5H,2-4,8H2,1H3,(H3,9,10,11);1H/t5-;/m0./s1 |
Activity & Biological Data
| Target | IC50: 70 μM (NOS)[1] |
|---|---|
| Additional Information | [1]. Pfeiffer S, et al. Inhibition of nitric oxide synthesis by NG-nitro-L-arginine methyl ester (L-NAME): requirement forbioactivation to the free acid, NG-nitro-L-arginine. Br J Pharmacol. 1996 Jul;118(6):1433-40. [2]. Kopincová J, et al. L-NAME in the cardiovascular system - nitric oxide synthase activator? Pharmacol Rep. 2012;64(3):511-20. [3]. Lo HC, et al. The Nitric Oxide Synthase Inhibitor NG-Nitro-L-Arginine Methyl Ester Diminishes the Immunomodulatory Effects of Parental Arginine in Rats with Subacute Peritonitis. PLoSOne. 2016 Mar 23;11(3):e0151973. [4]. Luo H, et al. Effect of nitric oxide synthase inhibitor L-NAME on fear extinction in rats: a task-dependent effect. Neurosci Lett. 2014 Jun 20;572:13-8. [5]. Ocsan RJ, et al. Chronic NG-nitro-l-arginine methyl ester (L-NAME) administration in C57BL/6J mice induces a sustained decrease in c-kit positive cells during development of cardiac hypertrophy. J Physiol Pharmacol. 2013 Dec;64(6):727-36. |
Frequently Asked Questions
What is the CAS number of Nω-Nitro-L-arginine methyl ester hydrochloride?
The CAS number of Nω-Nitro-L-arginine methyl ester hydrochloride is 51298-62-5.
What are the molecular formula and molecular weight of Nω-Nitro-L-arginine methyl ester hydrochloride?
Nω-Nitro-L-arginine methyl ester hydrochloride has molecular formula C7H16ClN5O4 and molecular weight 269.69 g/mol.
Which suppliers offer Nω-Nitro-L-arginine methyl ester hydrochloride?
1 supplier(s) listed; reference unit price ¥7.04–8.40 /g.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nω-Nitro-L-arginine methyl ester hydrochloride (CAS 51298-62-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48832-5 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.