Propylthiouracil
Also known as: 6-Propyl-2-thiouracil, 6-n-Propylthiouracil, 6-Propyl-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone, 2,3-Dihydro-6-propyl-2-thioxo-4(1H)-pyrimidinone, 4-Hydroxy-2-mercapto-6-propylpyrimidine, 2-Mercapto-4-hydroxy-6-n-propylpyrimidine, 6-Propyl-2-sulfanylpyrimidin-4-ol, PTU, PROPYCIL, PROTHYRAN
Propylthiouracil (CAS 51-52-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H10N2OS and a molecular weight of 170.232 g/mol. Key properties include a melting point of 218-220 °C(lit.), a boiling point of 355.2±34.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 168.6±25.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H351 — Suspected of causing cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 51-52-5
- Jingsj CID
- J-32773-2
- Molecular Formula
- C7H10N2OS
- Molecular Weight
- 170.232 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 218-220 °C(lit.) |
|---|---|
| Boiling Point | 355.2±34.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 168.6±25.7 °C |
| Exact Mass | 170.051376 |
| PSA | 80.74000 |
| LogP | -0.32 |
| Vapor Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive Index | 1.601 |
| Additional Property | 1.1 g/L |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H351 — Suspected of causing cancer
Activity & Biological Data
| Additional Information | [1]. Nakamura, H., et al., Comparison of methimazole and propylthiouracil in patients with hyperthyroidism caused by Graves' disease. J Clin Endocrinol Metab, 2007. 92(6): p. 2157-62. [2]. Taurog, A. and M.L. Dorris, A reexamination of the proposed inactivation of thyroid peroxidase in the rat thyroid by propylthiouracil. Endocrinology, 1989. 124(6): p. 3038-42. |
|---|
Customs & Trade Information
| HS Code | 2933599090 |
|---|---|
| Summary | 2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Propylthiouracil?
The CAS number of Propylthiouracil is 51-52-5.
What are the molecular formula and molecular weight of Propylthiouracil?
Propylthiouracil has molecular formula C7H10N2OS and molecular weight 170.232 g/mol.
Is Propylthiouracil hazardous?
Propylthiouracil has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H351 — Suspected of causing cancer.
What are the upstream and downstream products of Propylthiouracil?
For Propylthiouracil, Upstream Products: Methyl 3-oxohexanoate, Ethyl 3-oxohexanoate; Downstream Products: 2,4-Dichloro-6-propylpyrimidine.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Propylthiouracil (CAS 51-52-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-32773-2 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.