Ibudilast

异丁司特

Also known as: KC-404, Ketas, 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine, 2-Methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one, 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methyl-1-propanone, Ibudilastum

Ibudilast (CAS 50847-11-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C14H18N2O and a molecular weight of 230.305 g/mol. It is also known as KC-404, Ketas and 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine. Key properties include a melting point of 53-54°C and a density of 1.1±0.1 g/cm3. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 50847-11-5
Jingsj CID: J-1103161-3
Molecular Formula: C₁₄H₁₈N₂O
Chinese Name: 异丁司特
Molecular Weight: 230.305 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	53-54°C
Density	1.1±0.1 g/cm3
Exact Mass	230.141907
PSA	34.37000
LogP	3.34
Refractive Index	1.571
Additional Property	DMSO: 28 mg/mL, soluble

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information	[1]. Kishi, Y., et al., Ibudilast: A Non‐selective PDE Inhibitor with Multiple Actions on Blood Cells and the Vascular Wall. Cardiovascular drug reviews, 2001. 19(3): p. 215-225. [2]. Rolan, P., M. Hutchinson, and K. Johnson, Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease. Expert Opin Pharmacother, 2009. 10(17): p. 2897-904. [3]. Ledeboer, A., et al., Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs, 2007. 16(7): p. 935-50.

Additional Information

[1]. Kishi, Y., et al., Ibudilast: A Non‐selective PDE Inhibitor with Multiple Actions on Blood Cells and the Vascular Wall. Cardiovascular drug reviews, 2001. 19(3): p. 215-225. [2]. Rolan, P., M. Hutchinson, and K. Johnson, Ibudilast: a review of its pharmacology, efficacy and safety in respiratory and neurological disease. Expert Opin Pharmacother, 2009. 10(17): p. 2897-904. [3]. Ledeboer, A., et al., Ibudilast (AV-411). A new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes. Expert Opin Investig Drugs, 2007. 16(7): p. 935-50.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Ibudilast?

The CAS number of Ibudilast is 50847-11-5.

What are the molecular formula and molecular weight of Ibudilast?

Ibudilast has molecular formula C14H18N2O and molecular weight 230.305 g/mol.

Is Ibudilast hazardous?

Ibudilast has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Ibudilast?

For Ibudilast, Upstream Products: 1-Amino-2-methylpyridinium iodide, Isobutyric anhydride; Downstream Products: Isobutyric acid.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ibudilast (CAS 50847-11-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1103161-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.