Fenspiride hydrochloride

盐酸芬司必利

Also known as: Fenspiride HCl, Fenspiride (Hydrochloride), 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride, 2-Oxazolidinone-5-spiro-4'-[N-(2-phenylethyl)piperidine] hydrochloride, 1-Oxa-3,8-diazaspiro[4.5]decan-2-one, 8-(2-phenylethyl)-, hydrochloride (1:1), Depiride, Espiran, Fluiden, NDR-5998A, Pneumorel, Tegencia hydrochloride, Viarespan hydrochloride, 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro(4.5)decan-2-one hydrochloride

Fenspiride hydrochloride (CAS 5053-08-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C15H21ClN2O2 and a molecular weight of 296.79200 g/mol. It is also known as Fenspiride HCl, Fenspiride (Hydrochloride) and 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one hydrochloride. Key properties include a melting point of 235-238ºC (dec.), a boiling point of 474.3ºC at 760mmHg, a density of 1.19g/cm3 and a flash point of 240.6ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H332 — Harmful if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
5053-08-7
Jingsj CID
J-1987370-5
Molecular Formula
C15H21ClN2O2
Chinese Name
盐酸芬司必利
Molecular Weight
296.79200 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point235-238ºC (dec.)
Boiling Point474.3ºC at 760mmHg
Density1.19g/cm3
Flash Point240.6ºC
Exact Mass296.12900
PSA41.57000
LogP2.87220
Appearancepowder | white
Storage ConditionsRefrigerator

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H312 — Harmful in contact with skin
  • H332 — Harmful if inhaled

Activity & Biological Data

Additional Information[1]. Lebedenko AA, Mal'tsev SV. .[The efficacy of application of fenspiride (erespal) for the treatment of exacerbation of bronchial asthma in children.] Vestn Otorinolaringol. 2011;(4):66-67. [2]. Khawaja AM, Liu YC, Rogers DF. et al.Effect of fenspiride, a non-steroidal antiinflammatory agent, on neurogenic mucus secretion in ferret trachea in vitro. Pulm Pharmacol Ther. 1999;12(6):363-8. [3]. Zielnik-Jurkiewicz B, Jurkiewicz D. et al. Usefulness of fenspiride in the treatment of acute otitis media in children. Pol Merkur Lekarski. 2005 Jun;18(108):624-8. [4]. Bee D, Laude EA, Emery CJ, Howard P. Effect of fenspiride on pulmonary function in the rat and guinea pig. Clin Sci (Lond). 1995 Mar;88(3):325-30. [5]. Fenspiride

Frequently Asked Questions

What is the CAS number of Fenspiride hydrochloride?

The CAS number of Fenspiride hydrochloride is 5053-08-7.

What are the molecular formula and molecular weight of Fenspiride hydrochloride?

Fenspiride hydrochloride has molecular formula C15H21ClN2O2 and molecular weight 296.79200 g/mol.

Is Fenspiride hydrochloride hazardous?

Fenspiride hydrochloride has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H332 — Harmful if inhaled.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Fenspiride hydrochloride (CAS 5053-08-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1987370-5 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.