Kavain
醉椒素
Also known as: (+)-kavain, (6R)-4-Methoxy-6-[(E)-2-phenylvinyl]-5,6-dihydro-2H-pyran-2-one, (6R)-4-methoxy-6-[(E)-2-phenylethenyl]-5,6-dihydro-2H-pyran-2-one, (R)-5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one, (R)-kavain, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-, (6R)-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)-, 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)-, 4-Methoxy-6-(b-phenylvinyl)-5,6-dihydro-a-pyrone, 4-Methoxy-6-(β-phenylvinyl)-5,6-dihydro-α-pyrone, 4-Methoxy-6-styryl-5,6-dihydro-a-pyrone, 5,6-Dihydro-4-methoxy-6-styryl-2-pyron, 5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one, 5-Hydroxy-3-methoxy-7-phenyl-2,6-heptadienoic Acid d-Lactone, D-Kawain, Gonosan, Kavain, L-KAWAIN, Neuronika, [R-(E)]-5,6-Dihydro-4-methoxy-6-(2-phenylethenyl)-2H-pyran-2-one
Kavain (CAS 500-64-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C14H14O3 and a molecular weight of 230.259 g/mol. It is also known as (+)-kavain, (6R)-4-Methoxy-6-[(E)-2-phenylvinyl]-5,6-dihydro-2H-pyran-2-one and (6R)-4-methoxy-6-[(E)-2-phenylethenyl]-5,6-dihydro-2H-pyran-2-one. Key properties include a melting point of 142-148ºC, a boiling point of 432.6±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 184.6±23.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 500-64-1
- Jingsj CID
- J-1977436-7
- Molecular Formula
- C14H14O3
- Chinese Name
- 醉椒素
- Molecular Weight
- 230.259 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 142-148ºC |
|---|---|
| Boiling Point | 432.6±45.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 184.6±23.3 °C |
| Exact Mass | 230.094299 |
| PSA | 35.53000 |
| LogP | 1.69 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.565 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | Na+, Ca2+ channel[1]. α4β2δ GABAA receptor[2]. |
|---|---|
| Additional Information | [1]. Bradić I, et al. [Hirschsprung's disease -- therapy and results]. Acta Chir Iugosl. 1975;22(2):183-95. [2]. Chua HC, et al. Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism. PLoS One. 2016 Jun 22;11(6):e0157700. [3]. G. Boonen, et al. In vivo Effects of the Kavapyrones (+)-Dihydromethysticin and (±)-Kavain on Dopamine, 3,4-Dihydroxyphenylacetic Acid, Serotonin and 5-Hydroxyindoleacetic Acid Levels in Striatal and Cortical Brain Regions. Planta Medica 64 (1998) 507-510. [4]. Tang X, et al. Kavain Inhibition of LPS-Induced TNF-α via ERK/LITAF. Toxicol Res (Camb). 2016 Jan 1;5(1):188-196. |
Customs & Trade Information
| HS Code | 2932999099 |
|---|---|
| Summary | 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Kavain?
The CAS number of Kavain is 500-64-1.
What are the molecular formula and molecular weight of Kavain?
Kavain has molecular formula C14H14O3 and molecular weight 230.259 g/mol.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Kavain (CAS 500-64-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1977436-7 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.