Triprolidine

曲普利啶

Also known as: (E)-2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine, (E)-1-(2-pyridyl)-3-pyrrolidin-1-yl-1-p-tolylpropene, 2-[(E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine, trans-1-(2-Pyridyl)-3-pyrrolidino-1-p-tolylprop-1-ene, Triprolidin, Tripyrolidine, NCI-C61450, EINECS 207-627-0, MFCD00038040

Triprolidine (CAS 486-12-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H22N2 and a molecular weight of 278.39100 g/mol. It is also known as (E)-2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine, (E)-1-(2-pyridyl)-3-pyrrolidin-1-yl-1-p-tolylpropene and 2-[(E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]pyridine. Key properties include a melting point of 126-130°C, a boiling point of 435.4ºC at 760 mmHg, a density of 1.061 g/cm3 and a flash point of 217.1ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 486-12-4
Jingsj CID: J-1329388-4
Molecular Formula: C₁₉H₂₂N₂
Chinese Name: 曲普利啶
Molecular Weight: 278.39100 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	126-130°C
Boiling Point	435.4ºC at 760 mmHg
Density	1.061 g/cm3
Flash Point	217.1ºC
Exact Mass	278.17800
PSA	16.13000
LogP	3.85540
Vapor Pressure	6.16E-09mmHg at 25°C

Activity & Biological Data

Additional Information	[1]. Szeberényi JB, et, al. Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation. Immunol Lett. 2001 Apr 2;76(3):175-82. [2]. Tzeng JI, et, al. Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats. J Pharm Pharmacol. 2018 Dec;70(12):1654-1661. [3]. Deal DL, Chandrasurin P, Shockcor J, Minick DJ, Findlay JW, McNulty MJ. Disposition and metabolism of triprolidine in mice. Drug Metab Dispos. 1992 Nov-Dec;20(6):920-7.

Additional Information

[1]. Szeberényi JB, et, al. Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation. Immunol Lett. 2001 Apr 2;76(3):175-82. [2]. Tzeng JI, et, al. Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats. J Pharm Pharmacol. 2018 Dec;70(12):1654-1661. [3]. Deal DL, Chandrasurin P, Shockcor J, Minick DJ, Findlay JW, McNulty MJ. Disposition and metabolism of triprolidine in mice. Drug Metab Dispos. 1992 Nov-Dec;20(6):920-7.

Frequently Asked Questions

What is the CAS number of Triprolidine?

The CAS number of Triprolidine is 486-12-4.

What are the molecular formula and molecular weight of Triprolidine?

Triprolidine has molecular formula C19H22N2 and molecular weight 278.39100 g/mol.

What are the upstream and downstream products of Triprolidine?

For Triprolidine, Downstream Products: Triprolidine hydrochloride.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Triprolidine (CAS 486-12-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1329388-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.