Ajmalicine

Also known as: Raubasine, δ-Yohimbine, Tetrahydroserpentine, Vincain, Vincaine, Vincein, Vinceine, Sarpan, Tensyl, Lamuran, Ranitol, Raubasil, Rauvasan, Circolene, Hydrosarpan, Isoarteril, Raubaserp, Raumalina, Py-tetrahydroserpentine, Ajmalicin

Ajmalicine (CAS 483-04-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C21H24N2O3 and a molecular weight of 352.427 g/mol. Key properties include a melting point of 258°C (rough estimate), a boiling point of 524.0±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 270.7±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 483-04-5
Jingsj CID: J-18871-6
Molecular Formula: C₂₁H₂₄N₂O₃
Molecular Weight: 352.427 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	258°C (rough estimate)
Boiling Point	524.0±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	270.7±30.1 °C
Exact Mass	352.178680
PSA	54.56000
LogP	2.88
Vapor Pressure	0.0±1.4 mmHg at 25°C
Refractive Index	1.656

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. Wink, Michael; Roberts, M. W. (1998). Alkaloids: biochemistry, ecology, and medicinal applications. New York: Plenum Press. ISBN 0-306-45465-3. [2]. Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5. [3]. Pereira DM, et al. Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine. 2010 Jul;17(8-9):646-52. [4]. • Demichel P, et al. Effects of raubasine stereoisomers on pre- and postsynaptic alpha-adrenoceptors in the rat vas deferens. Br J Pharmacol. 1984 Oct;83(2):505-10

Additional Information

[1]. Wink, Michael; Roberts, M. W. (1998). Alkaloids: biochemistry, ecology, and medicinal applications. New York: Plenum Press. ISBN 0-306-45465-3. [2]. Roquebert J, et al. Inhibition of the alpha 1 and alpha 2-adrenoceptor-mediated pressor response in pithed rats by raubasine, tetrahydroalstonine and akuammigine. Eur J Pharmacol. 1984 Oct 30;106(1):203-5. [3]. Pereira DM, et al. Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission. Phytomedicine. 2010 Jul;17(8-9):646-52. [4]. • Demichel P, et al. Effects of raubasine stereoisomers on pre- and postsynaptic alpha-adrenoceptors in the rat vas deferens. Br J Pharmacol. 1984 Oct;83(2):505-10

Frequently Asked Questions

What is the CAS number of Ajmalicine?

The CAS number of Ajmalicine is 483-04-5.

What are the molecular formula and molecular weight of Ajmalicine?

Ajmalicine has molecular formula C21H24N2O3 and molecular weight 352.427 g/mol.

Is Ajmalicine hazardous?

Ajmalicine has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Ajmalicine?

For Ajmalicine, Upstream Products: Methanol, 1-tert-Butoxy-N,N,N',N'-tetramethylmethanediamine, Secologanin.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Ajmalicine (CAS 483-04-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18871-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.