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Chrysophanol

Also known as: Chrysophanic acid, 1,8-Dihydroxy-3-methylanthraquinone, 1,8-Dihydroxy-3-methylanthracene-9,10-dione, 3-Methyl-1,8-dihydroxyanthraquinone, C.I. 75400, C.I. Natural Yellow 23

Chrysophanol (CAS 481-74-3) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C15H10O4 and a molecular weight of 254.238 g/mol. Key properties include a melting point of 194-198 °C, a boiling point of 489.5±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 263.9±25.2 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
481-74-3
Jingsj CID
J-2725-6
Molecular Formula
C15H10O4
Molecular Weight
254.238 g/mol
Category
Alcohols
Last updated
8/21/2026

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Physicochemical Properties

Melting Point194-198 °C
Boiling Point489.5±45.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point263.9±25.2 °C
Exact Mass254.057907
PSA74.60000
LogP5.03
Vapor Pressure0.0±1.3 mmHg at 25°C
Refractive Index1.710
Additional Property<0.1 g/100 mL at 18 ºC

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation

Activity & Biological Data

TargetEGFR
Additional Information[1]. Lee MS, et al. Chrysophanic acid blocks proliferation of colon cancer cells by inhibiting EGFR/mTOR pathway. Phytother Res. 2011 Jun;25(6):833-7. [2]. Lim H, et al. Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro. Front Pharmacol. 2016 Dec 8;7:476.

Customs & Trade Information

HS Code2942000000

Frequently Asked Questions

What is the CAS number of Chrysophanol?

The CAS number of Chrysophanol is 481-74-3.

What are the molecular formula and molecular weight of Chrysophanol?

Chrysophanol has molecular formula C15H10O4 and molecular weight 254.238 g/mol.

Is Chrysophanol hazardous?

Chrysophanol has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Chrysophanol?

For Chrysophanol, Upstream Products: Chrysophanol 8-O-β-D-glucopyranoside, 1,8-Dimethoxy-3-methylanthraquinone, Aloe-emodin; Downstream Products: Rhein, Aloe-emodin, 4-Hydroxyisophthalic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Chrysophanol (CAS 481-74-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-2725-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.