Retrorsine

倒千里光碱

Also known as: isatidine, beta-longilobine, retrorsin, 12,18-dihydroxysenecionan-11,16-dione, cis-retronecic acid ester of retronecine, NSC 107659

Retrorsine (CAS 480-54-6) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C18H25NO6 and a molecular weight of 351.394 g/mol. It is also known as isatidine, beta-longilobine and retrorsin. Key properties include a melting point of 208-211ºC(lit.), a boiling point of 583.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 306.5±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 480-54-6
Jingsj CID: J-38737-8
Molecular Formula: C₁₈H₂₅NO₆
Chinese Name: 倒千里光碱
Molecular Weight: 351.394 g/mol
Category: Organic Bases
Last updated: 8/21/2026

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	208-211ºC(lit.)
Boiling Point	583.2±50.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	306.5±30.1 °C
Exact Mass	351.168182
PSA	96.30000
LogP	-0.14
Vapor Pressure	0.0±3.7 mmHg at 25°C
Refractive Index	1.590

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H300

Activity & Biological Data

Additional Information	[1]. F J Cubero, et al. Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine. Cell Prolif. 2005 Jun;38(3):137-46. [2]. F J Cubero, et al. Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine. Cell Prolif. 2005 Jun;38(3):137-46. [3]. Yao Lu, et al. Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids. J Environ Sci Health C Toxicol Carcinog. 2020;38(2):169-185.

Additional Information

[1]. F J Cubero, et al. Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine. Cell Prolif. 2005 Jun;38(3):137-46. [2]. F J Cubero, et al. Hepatic proliferation in Gunn rats transplanted with hepatocytes: effect of retrorsine and tri-iodothyronine. Cell Prolif. 2005 Jun;38(3):137-46. [3]. Yao Lu, et al. Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids. J Environ Sci Health C Toxicol Carcinog. 2020;38(2):169-185.

Frequently Asked Questions

What is the CAS number of Retrorsine?

The CAS number of Retrorsine is 480-54-6.

What are the molecular formula and molecular weight of Retrorsine?

Retrorsine has molecular formula C18H25NO6 and molecular weight 351.394 g/mol.

Is Retrorsine hazardous?

Retrorsine has GHS signal word Danger and hazard statements H300.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Retrorsine (CAS 480-54-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-38737-8 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.