(-)-Demecolcine
秋水仙胺
Also known as: Demecolcine, Colcemid, Colcemide, N-Deacetyl-N-methylcolchicine, Substance F, (-)-Demecolcine
(-)-Demecolcine (CAS 477-30-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C21H25NO5 and a molecular weight of 371.427 g/mol. It is also known as Demecolcine, Colcemid and Colcemide. Key properties include a melting point of 73-75ºC, a boiling point of 625.5±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 332.1±31.5 °C. It is classified under GHS with signal word Danger and hazard statements H300. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 477-30-5
- Jingsj CID
- J-4235-4
- Molecular Formula
- C21H25NO5
- Chinese Name
- 秋水仙胺
- Molecular Weight
- 371.427 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 73-75ºC |
|---|---|
| Boiling Point | 625.5±55.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 332.1±31.5 °C |
| Exact Mass | 371.173279 |
| PSA | 66.02000 |
| LogP | 1.52 |
| Vapor Pressure | 0.0±1.8 mmHg at 25°C |
| Refractive Index | 1.582 |
GHS Safety & Compliance
- H300
Activity & Biological Data
| Additional Information | [1]. T Tsuchida, et al. Colcemid-induced apoptosis of cultured human glioma: electron microscopic and confocal laser microscopic observation of cells sorted in different phases of cell cycle. Cytometry. 1998 Apr 1;31(4):295-9. [2]. Ashley M Rozario, et al. Ultra-Low Colcemid Doses Induce Microtubule Dysfunction as Revealed by Super-Resolution Microscopy. Bioexiv. |
|---|
Frequently Asked Questions
What is the CAS number of (-)-Demecolcine?
The CAS number of (-)-Demecolcine is 477-30-5.
What are the molecular formula and molecular weight of (-)-Demecolcine?
(-)-Demecolcine has molecular formula C21H25NO5 and molecular weight 371.427 g/mol.
Is (-)-Demecolcine hazardous?
(-)-Demecolcine has GHS signal word Danger and hazard statements H300.
What are the upstream and downstream products of (-)-Demecolcine?
For (-)-Demecolcine, Upstream Products: Colchicine, Colchiceine, Trimethylcolchicinic acid.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "(-)-Demecolcine (CAS 477-30-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-4235-4 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.