Betulin

Also known as: Betulinol, Betulol, Trochol, Lup-20(29)-ene-3β,28-diol, (3β)-Lup-20(29)-ene-3,28-diol, 3β,28-Dihydroxylup-20(29)-ene, Betula camphor

Betulin (CAS 473-98-3) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C30H50O2 and a molecular weight of 442.717 g/mol. Key properties include a melting point of 256-257 °C(lit.), a boiling point of 522.3±23.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 210.9±17.2 °C. It is classified under GHS with signal word Warning and hazard statements H371 — May cause damage to organs. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 473-98-3
Jingsj CID: J-18862-5
Molecular Formula: C₃₀H₅₀O₂
Molecular Weight: 442.717 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	256-257 °C(lit.)
Boiling Point	522.3±23.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	210.9±17.2 °C
Exact Mass	442.381073
PSA	40.46000
LogP	9.01
Vapor Pressure	0.0±3.1 mmHg at 25°C
Refractive Index	1.525

GHS Safety & Compliance

Health HazardSignal word: Warning

H371 — May cause damage to organs

Activity & Biological Data

Target	IC50: 14.5 μM (SREBP, K562 cell), 74.1 μM (SREBP, HeLa cell), 17.1 μM (SREBP, GOTO cell)[1], 21.09 μM (SREBP, 181P cell), 20.62 μM (SREBP, HeLa cell)[2]
Additional Information	[1]. Król SK, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189. [2]. Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14(4):1639-51. [3]. Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111.

Target

IC50: 14.5 μM (SREBP, K562 cell), 74.1 μM (SREBP, HeLa cell), 17.1 μM (SREBP, GOTO cell)[1], 21.09 μM (SREBP, 181P cell), 20.62 μM (SREBP, HeLa cell)[2]

Additional Information

[1]. Król SK, et al. Comprehensive review on betulin as a potent anticancer agent. Biomed Res Int. 2015;2015:584189. [2]. Drag M, et al. Comparision of the Cytotoxic Effects of Birch Bark Extract, Betulin and Betulinic Acid Towards Human Gastric Carcinoma and Pancreatic Carcinoma Drug-sensitive and Drug-Resistant Cell Lines. Molecules. 2009 Apr 24;14(4):1639-51. [3]. Ma C, et al. Protective effect of betulin on cognitive decline in streptozotocin (STZ)-induced diabetic rats. Neurotoxicology. 2016 Dec;57:104-111.

Customs & Trade Information

HS Code	29181985

Frequently Asked Questions

What is the CAS number of Betulin?

The CAS number of Betulin is 473-98-3.

What are the molecular formula and molecular weight of Betulin?

Betulin has molecular formula C30H50O2 and molecular weight 442.717 g/mol.

Is Betulin hazardous?

Betulin has GHS signal word Warning and hazard statements H371 — May cause damage to organs.

What are the upstream and downstream products of Betulin?

For Betulin, Upstream Products: Betulin diacetate, Betulinic acid methyl ester, Betulinic acid; Downstream Products: Betulinic acid, Betulinaldehyde, Betulonic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Betulin (CAS 473-98-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-18862-5 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.