Glycyrrhetinic acid

Also known as: Enoxolone, 18β-Glycyrrhetinic acid, 18-beta-Glycyrrhetinic acid, 18β-Glycyrrhetic acid, Uralenic acid, Biosone, Arthrodont, Glycyrrhetic acid, 3β-Hydroxy-11-oxoolean-12-en-30-oic acid, (3β,20β)-3-Hydroxy-11-oxoolean-12-en-29-oic acid, (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid, Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3β,20β)-, GM 1658, PO 12, STX 352, Glycyrrhetin

Glycyrrhetinic acid (CAS 471-53-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C30H46O4 and a molecular weight of 470.684 g/mol. Key properties include a melting point of 292 - 295ºC, a boiling point of 588.3±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 323.7±26.6 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H319 — Causes serious eye irritation. It is listed by 1 supplier, from 44.00 to 44.00 CNY per 25g. Record last updated Aug 21, 2026.

CAS No.: 471-53-4
Jingsj CID: J-43520-4
Molecular Formula: C₃₀H₄₆O₄
Molecular Weight: 470.684 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Jingkang In Stock	97% 25g	¥1,100.00	$6.58 /gBest ¥44.00/g CNY	CN China MOQ 25g	Visit Website

Physicochemical Properties

Melting Point	292 - 295ºC
Boiling Point	588.3±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	323.7±26.6 °C
Exact Mass	470.339600
PSA	74.60000
LogP	6.57
Vapor Pressure	0.0±3.7 mmHg at 25°C
Refractive Index	1.563

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed
H319 — Causes serious eye irritation

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Huang RY, et al. 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. PLoS One. 2014 Apr 2;9(4):e93690. [2]. Zhou J, et al. 18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination. Sci Rep. 2015 Sep 2;5:13713. [3]. Yang G, et al. Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats. Evid Based Complement Alternat Med. 2017;2017:3470320.

Target

Human Endogenous Metabolite

Additional Information

[1]. Huang RY, et al. 18β-Glycyrrhetinic acid suppresses cell proliferation through inhibiting thromboxane synthase in non-small cell lung cancer. PLoS One. 2014 Apr 2;9(4):e93690. [2]. Zhou J, et al. 18β-glycyrrhetinic acid suppresses experimental autoimmune encephalomyelitis through inhibition of microglia activation and promotion of remyelination. Sci Rep. 2015 Sep 2;5:13713. [3]. Yang G, et al. Protective Effect of 18β-Glycyrrhetinic Acid against Triptolide-Induced Hepatotoxicity in Rats. Evid Based Complement Alternat Med. 2017;2017:3470320.

Customs & Trade Information

HS Code	2918990090
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Glycyrrhetinic acid?

The CAS number of Glycyrrhetinic acid is 471-53-4.

What are the molecular formula and molecular weight of Glycyrrhetinic acid?

Glycyrrhetinic acid has molecular formula C30H46O4 and molecular weight 470.684 g/mol.

Which suppliers offer Glycyrrhetinic acid?

1 supplier(s) listed; reference unit price ¥44.00–44.00 /g.

Is Glycyrrhetinic acid hazardous?

Glycyrrhetinic acid has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Glycyrrhetinic acid?

For Glycyrrhetinic acid, Upstream Products: Glycyrrhizic acid, Glycyrrhizic acid ammonium salt, Glycyrrhetic acid 3-O-glucuronide; Downstream Products: Glycyrrhetic acid 3-O-glucuronide, Stearyl glycyrrhetinate, 18α-Glycyrrhetinic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Glycyrrhetinic acid (CAS 471-53-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-43520-4 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.