Doxylamine

多西拉敏

Also known as: 2-[alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl]pyridine, 2-dimethylaminoethoxyphenylmethyl-2-picoline, Dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine, Dossilamina, Doxilminio, Doxylaminum, Ethanamine, N,N-dimethyl-2-[(1R)-1-phenyl-1-(2-pyridinyl)ethoxy]-, N,N-Dimethyl-2-[(1R)-1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine, N,N-Dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]ethanamine, N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine, NCI C60684, Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether, Pyridine, 2-[alpha-[2-(dimethylamino)ethoxy]-alpha-methylbenzyl]-, doxilamina

Doxylamine (CAS 469-21-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C17H22N2O and a molecular weight of 270.37 g/mol. It is also known as 2-[alpha-(2-dimethylaminoethoxy)-alpha-methylbenzyl]pyridine, 2-dimethylaminoethoxyphenylmethyl-2-picoline and Dimethyl(2-(1-phenyl-1-(2-pyridyl)ethoxy)ethyl)amine. Key properties include a melting point of 25°C, a boiling point of 364.9ºC at 760 mmHg, a density of 1.043 g/cm3 and a flash point of 174.5ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 469-21-6
Jingsj CID: J-40568-3
Molecular Formula: C₁₇H₂₂N₂O
Chinese Name: 多西拉敏
Molecular Weight: 270.37 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	25°C
Boiling Point	364.9ºC at 760 mmHg
Density	1.043 g/cm3
Flash Point	174.5ºC
Exact Mass	270.17300
PSA	25.36000
LogP	2.92330
Refractive Index	1.5486 (estimate)
Storage Conditions	-20°C

Activity & Biological Data

Target	H1 Receptor
Additional Information	[1]. Sjöqvist F, Lasagna L. The hypnotic efficacy of doxylamine. Clin Pharmacol Ther. 1967;8(1):48-54. [2]. Hung CH, et al. Subcutaneous infiltration of doxylamine on cutaneous analgesia in rats. Pharmacol Rep. 2018;70(3):565-569. [3]. Jackson CD, Blackwell BN. Subchronic studies of doxylamine in B6C3F1 mice. Fundam Appl Toxicol. 1988;10(2):254-261.

Frequently Asked Questions

What is the CAS number of Doxylamine?

The CAS number of Doxylamine is 469-21-6.

What are the molecular formula and molecular weight of Doxylamine?

Doxylamine has molecular formula C17H22N2O and molecular weight 270.37 g/mol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Doxylamine (CAS 469-21-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-40568-3 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.