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Naloxone

Also known as: 17-allyl-4,5α-epoxy-3,14-dihydroxymorphinan-6-one, N-Allylnoroxymorphone, EN-1530, Narcan, Narcanti, Nalone, Naloxonum, Naloxona

Naloxone (CAS 465-65-6) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C19H21NO4 and a molecular weight of 327.37 g/mol. Key properties include a melting point of 184ºC, a boiling point of 532.8ºC at 760 mmHg, a density of 1.43 g/cm3 and a flash point of 276.1ºC. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H301 — Toxic if swallowed and H311 — Toxic in contact with skin. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
465-65-6
Jingsj CID
J-1340194-0
Molecular Formula
C19H21NO4
Molecular Weight
327.37 g/mol
Category
Ketones
Last updated
8/21/2026
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Physicochemical Properties

Melting Point184ºC
Boiling Point532.8ºC at 760 mmHg
Density1.43 g/cm3
Flash Point276.1ºC
Exact Mass327.14700
PSA70.00000
LogP1.23930
Storage Conditions2-8°C

GHS Safety & Compliance

Flammable / Acute Toxicity / Health HazardSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H370 — Causes damage to organs

Activity & Biological Data

Additional Information[1]. van Dorp E, et al. Naloxone treatment in opioid addiction: the risks and benefits. Expert Opin Drug Saf. 2007 Mar;6(2):125-32.

Frequently Asked Questions

What is the CAS number of Naloxone?

The CAS number of Naloxone is 465-65-6.

What are the molecular formula and molecular weight of Naloxone?

Naloxone has molecular formula C19H21NO4 and molecular weight 327.37 g/mol.

Is Naloxone hazardous?

Naloxone has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H301 — Toxic if swallowed; H311 — Toxic in contact with skin.

What are the upstream and downstream products of Naloxone?

For Naloxone, Upstream Products: Noroxymorphone, Allyl bromide, Vinylmagnesium bromide; Downstream Products: Noroxymorphone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Naloxone (CAS 465-65-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1340194-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.