1,1'-Binaphthyl-2,2'-diamine

Also known as: 2,2'-Diamino-1,1'-binaphthyl, 1,1'-Binaphthalene-2,2'-diamine, 1,1'-Bi(2-naphthalenamine), Racemic-2,2'-diamino-1,1'-binaphthyl, [1,1'-Binaphthalene]-2,2'-diamine, (±)-1,1'-Binaphthalene-2,2'-diamine, (±)-2,2'-Diamino-1,1'-binaphthalene, binaphthyldiamine

1,1'-Binaphthyl-2,2'-diamine (CAS 4488-22-6) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C20H16N2 and a molecular weight of 284.35 g/mol. Key properties include a melting point of 242-244ºC(lit.), a boiling point of 480.8±30.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 293.9±24.0 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 4488-22-6
Jingsj CID: J-25354-3
Molecular Formula: C₂₀H₁₆N₂
Molecular Weight: 284.35 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	242-244ºC(lit.)
Boiling Point	480.8±30.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	293.9±24.0 °C
Exact Mass	284.131348
PSA	52.04000
LogP	3.85
Appearance	slightly beige
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.775
Additional Property	Insoluble in water

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger

H302 — Harmful if swallowed
H318 — Causes serious eye damage

Activity & Biological Data

Additional Information	[1]. Kettle JG, et al. Discovery of AZD4625, a Covalent Allosteric Inhibitor of the Mutant GTPase KRASG12C. J Med Chem. 2022 May 12;65(9):6940-6952.

Frequently Asked Questions

What is the CAS number of 1,1'-Binaphthyl-2,2'-diamine?

The CAS number of 1,1'-Binaphthyl-2,2'-diamine is 4488-22-6.

What are the molecular formula and molecular weight of 1,1'-Binaphthyl-2,2'-diamine?

1,1'-Binaphthyl-2,2'-diamine has molecular formula C20H16N2 and molecular weight 284.35 g/mol.

Is 1,1'-Binaphthyl-2,2'-diamine hazardous?

1,1'-Binaphthyl-2,2'-diamine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H318 — Causes serious eye damage.

What are the upstream and downstream products of 1,1'-Binaphthyl-2,2'-diamine?

For 1,1'-Binaphthyl-2,2'-diamine, Upstream Products: 2-Naphthylamine, 2-Naphthol, 2,2'-dibromo-1,1'-binaphthalene; Downstream Products: (R)-(+)-2,2'-Diamino-1,1'-binaphthalene, (S)-(-)-1,1'-Binaphthyl-2,2'-diamine, 7H-Dibenzo[c,g]carbazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1,1'-Binaphthyl-2,2'-diamine (CAS 4488-22-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-25354-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.