Methyl difluoroacetate
Also known as: Methyl 2,2-difluoroacetate, Difluoroacetic acid methyl ester, 2,2-Difluoroacetic acid methyl ester, Methyldifluoroacetate, AKOS B020262, ART-CHEM-BB B020262
Methyl difluoroacetate (CAS 433-53-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C3H4F2O2 and a molecular weight of 110.060 g/mol. Key properties include a boiling point of 45.0±25.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of -16.9±18.1 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H302 — Harmful if swallowed and H312 — Harmful in contact with skin. It is listed by 2 suppliers, 1 of which publish reference prices, from 3.20 to 3.98 CNY. Record last updated Aug 21, 2026.
- CAS No.
- 433-53-4
- Jingsj CID
- J-1320310-0
- Molecular Formula
- C3H4F2O2
- Molecular Weight
- 110.060 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
| Supplier | Purity / Pack | Base Price | Unit Price | Origin | |
|---|---|---|---|---|---|
In Stock | >98.0%(GC) 500g | ¥1,598.00 | $0.48 /gBest ¥3.20/g CNY | CN China MOQ 500g | |
In Stock | >98.0%(GC) 100g | ¥398.00 | $0.6 /g ¥3.98/g CNY | CN China MOQ 100g | |
Made to Order | >98.0%(GC) 100g | - | - | CN China MOQ 100g |
Physicochemical Properties
| Boiling Point | 45.0±25.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | -16.9±18.1 °C |
| Exact Mass | 110.017937 |
| PSA | 26.30000 |
| LogP | -0.12 |
| Vapor Pressure | 354.3±0.1 mmHg at 25°C |
| Refractive Index | 1.312 |
GHS Safety & Compliance
- H226 — Flammable liquid and vapour
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H332 — Harmful if inhaled
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Customs & Trade Information
| HS Code | 2915900090 |
|---|---|
| Summary | 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Methyl difluoroacetate?
The CAS number of Methyl difluoroacetate is 433-53-4.
What are the molecular formula and molecular weight of Methyl difluoroacetate?
Methyl difluoroacetate has molecular formula C3H4F2O2 and molecular weight 110.060 g/mol.
Which suppliers offer Methyl difluoroacetate?
2 supplier(s) listed; reference unit price ¥3.20–3.98 /g.
Is Methyl difluoroacetate hazardous?
Methyl difluoroacetate has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H302 — Harmful if swallowed; H312 — Harmful in contact with skin.
What are the upstream and downstream products of Methyl difluoroacetate?
For Methyl difluoroacetate, Upstream Products: Methanol, 1,1,2,2-Tetrafluoroethyl methyl ether, Methyl dichloroacetate; Downstream Products: Difluoroacetic acid, 2,2-Difluoroethanol, 1,1-difluoropentane-2,4-dione.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Methyl difluoroacetate (CAS 433-53-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1320310-0 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.