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Nabumetone

Also known as: 4-(6-Methoxy-2-naphthyl)-2-butanone, 4-(6-Methoxynaphthalen-2-yl)butan-2-one, Relafen, Relifex, Arthaxan, Nabumeton, Nabuser, Relif, Relifen, brl147777

Nabumetone (CAS 42924-53-8) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C15H16O2 and a molecular weight of 228.286 g/mol. Key properties include a melting point of 80-81ºC, a boiling point of 371.1±17.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 165.4±14.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
42924-53-8
Jingsj CID
J-1983590-5
Molecular Formula
C15H16O2
Molecular Weight
228.286 g/mol
Category
Ketones
Last updated
8/21/2026

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Physicochemical Properties

Melting Point80-81ºC
Boiling Point371.1±17.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point165.4±14.5 °C
Exact Mass228.115036
PSA26.30000
LogP2.82
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.576
Storage ConditionsRefrigerator

Activity & Biological Data

TargetCOX-2
Additional Information[1]. Vural F, et al. Cyclo-oxygenase 2 inhibitor, nabumetone, inhibits proliferation in chronic myeloid leukemia cell lines. Leuk Lymphoma. 2005 May;46(5):753-6. [2]. Melarange R, et al. Anti-inflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6MNA (6-methoxy-2-naphthylacetic acid): comparison with indomethacin. Agents Actions. 1992;Spec No:C82-3.

Customs & Trade Information

HS Code2914509090
SummaryHS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Nabumetone?

The CAS number of Nabumetone is 42924-53-8.

What are the molecular formula and molecular weight of Nabumetone?

Nabumetone has molecular formula C15H16O2 and molecular weight 228.286 g/mol.

What are the upstream and downstream products of Nabumetone?

For Nabumetone, Upstream Products: 3-Buten-2-one, 4-hydroxy-4-(6-methoxy-2-naphthalenyl)-, 3-Buten-2-ol, 2-Bromo-6-methoxynaphthalene; Downstream Products: 6-Methoxy-2-naphthaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Nabumetone (CAS 42924-53-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1983590-5 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.