1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

Also known as: DOPE, 1,2-Dioleoyl-sn-glycero-3-phosphatidylethanolamine, 1,2-Dioleoyl-sn-glycerol-3-phosphoethanolamine, Dioleoyl phosphoethanolamine, L-α-Phosphatidylethanolamine, dioleoyl, 18:1 PE, 3-sn-Phosphatidylethanolamine, 1,2-dioleoyl, COATSOME ME-8181

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (CAS 4004-05-1) is a compound in the Solvents category listed in the Jingsj chemical database. It has the molecular formula C41H78NO8P and a molecular weight of 744.034 g/mol. Key properties include a melting point of 200 °C, a boiling point of 759.2±70.0 °C at 760 mmHg, a density of 1.008g/cm3 and a flash point of 413.0±35.7 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 4004-05-1
Jingsj CID: J-42474-1
Molecular Formula: C₄₁H₇₈NO₈P
Molecular Weight: 744.034 g/mol
Category: Solvents
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	200 °C
Boiling Point	759.2±70.0 °C at 760 mmHg
Density	1.008g/cm3
Flash Point	413.0±35.7 °C
Exact Mass	743.546509
PSA	144.19000
LogP	14.79
Vapor Pressure	0.0±5.5 mmHg at 25°C
Refractive Index	1.484

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger

H302 — Harmful if swallowed
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H331 — Toxic if inhaled
H336 — May cause drowsiness or dizziness
H351 — Suspected of causing cancer
H372 — Causes damage to organs through prolonged exposure

Activity & Biological Data

Target	IC50: helper lipid for liposome[1]
Additional Information	[1]. Uemura Y, et al. The efficiency of lipid nanoparticles with an original cationic lipid as a siRNA delivery system for macrophages and dendritic cells.Pharm Dev Technol. 2019 Mar;24(3):263-268.

Customs & Trade Information

HS Code	2931900090
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine?

The CAS number of 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine is 4004-05-1.

What are the molecular formula and molecular weight of 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine?

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine has molecular formula C41H78NO8P and molecular weight 744.034 g/mol.

Is 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine hazardous?

1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine?

For 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, Upstream Products: 1,2-dioleoyl-sn-glycero-3-phosphocholine, Ethanolamine, 1,2-Dioleoyl-sn-glycerol; Downstream Products: 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine (CAS 4004-05-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42474-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.