BCTC

Also known as: 4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide, N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide, 4-(3-Chloro-2-pyridinyl)-N-[4-(2-methyl-2-propanyl)phenyl]-1-piperazinecarboxamide, 1-Piperazinecarboxamide, 4-(3-chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-, BCTC (TRPV1 antagonist)

BCTC (CAS 393514-24-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C20H25ClN4O and a molecular weight of 372.892 g/mol. Key properties include a boiling point of 561.6±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 293.4±30.1 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 393514-24-4
Jingsj CID: J-1977836-1
Molecular Formula: C₂₀H₂₅ClN₄O
Molecular Weight: 372.892 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	561.6±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	293.4±30.1 °C
Exact Mass	372.171692
PSA	48.47000
LogP	4.08
Vapor Pressure	0.0±1.5 mmHg at 25°C
Refractive Index	1.610
Storage Conditions	2-8℃

GHS Safety & Compliance

IrritantSignal word: Warning

H302 — Harmful if swallowed

Activity & Biological Data

Additional Information	[1]. Liu T, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016 Jan;11(1):182-188. [2]. Pomonis JD, et al. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflamm [3]. Valenzano KJ, et al. N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic pro

Additional Information

[1]. Liu T, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016 Jan;11(1):182-188. [2]. Pomonis JD, et al. N-(4-Tertiarybutylphenyl)-4-(3-cholorphyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: II. in vivo characterization in rat models of inflamm [3]. Valenzano KJ, et al. N-(4-tertiarybutylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine -1(2H)-carbox-amide (BCTC), a novel, orally effective vanilloid receptor 1 antagonist with analgesic properties: I. in vitro characterization and pharmacokinetic pro

Frequently Asked Questions

What is the CAS number of BCTC?

The CAS number of BCTC is 393514-24-4.

What are the molecular formula and molecular weight of BCTC?

BCTC has molecular formula C20H25ClN4O and molecular weight 372.892 g/mol.

Is BCTC hazardous?

BCTC has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "BCTC (CAS 393514-24-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1977836-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.