Penbutolol

喷布洛尔

Also known as: (-)-Penbutolol, (S)-Penbutolol, Levopenbutolol, Betapressin, HOE 893, HOE 893D, 1-(2-Cyclopentylphenoxy)-3-[(1,1-dimethylethyl)amino]-2-propanol

Penbutolol (CAS 38363-40-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H29NO2 and a molecular weight of 291.42800 g/mol. It is also known as (-)-Penbutolol, (S)-Penbutolol and Levopenbutolol. Key properties include a boiling point of 438.2ºC at 760mmHg, a density of 1.03g/cm3 and a flash point of 218.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 38363-40-5
Jingsj CID: J-1958333-2
Molecular Formula: C₁₈H₂₉NO₂
Chinese Name: 喷布洛尔
Molecular Weight: 291.42800 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	438.2ºC at 760mmHg
Density	1.03g/cm3
Flash Point	218.8ºC
Exact Mass	291.22000
PSA	41.49000
LogP	3.86290
Refractive Index	1.527

Activity & Biological Data

Target	β-adrenoceptor, 5-HT receptor[1][2]
Additional Information	[1]. Hjorth S, et al. In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. J Pharmacol Exp Ther. 1993 May;265(2):707-12. [2]. M E Castro, et al. Affinity of (±)-Pindolol, (-)-Penbutolol, and (-)-Tertatolol for Pre- and Postsynaptic Serotonin 5-HT1A Receptors in Human and Rat Brain. Journal of Neurochemistry, Volume 75, Issue 2, p. 755-762.

Target

β-adrenoceptor, 5-HT receptor[1][2]

Additional Information

[1]. Hjorth S, et al. In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol. J Pharmacol Exp Ther. 1993 May;265(2):707-12. [2]. M E Castro, et al. Affinity of (±)-Pindolol, (-)-Penbutolol, and (-)-Tertatolol for Pre- and Postsynaptic Serotonin 5-HT1A Receptors in Human and Rat Brain. Journal of Neurochemistry, Volume 75, Issue 2, p. 755-762.

Frequently Asked Questions

What is the CAS number of Penbutolol?

The CAS number of Penbutolol is 38363-40-5.

What are the molecular formula and molecular weight of Penbutolol?

Penbutolol has molecular formula C18H29NO2 and molecular weight 291.42800 g/mol.

What are the upstream and downstream products of Penbutolol?

For Penbutolol, Upstream Products: 2-Cyclopentylphenol, tert-Butylamine, Cyclopentanol.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Penbutolol (CAS 38363-40-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1958333-2 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.