Bis(cyclohexanone)oxaldihydrazone

Also known as: Cuprizone, oxalic bis(cyclohexylidenehydrazide), Dicyclohexanoneoxaly dihydrazone, Bis(cyclohexanone)oxalyldihydrazone, Oxalic acid bis(cyclohexylidenehydrazide), Cupferazone, Cuprizon, N',N'-Dicyclohexylideneethanedihydrazide, N,N'-bis(cyclohexylideneamino)oxamide

Bis(cyclohexanone)oxaldihydrazone (CAS 370-81-0) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C14H22N4O2 and a molecular weight of 278.350 g/mol. Key properties include a melting point of 210-214 °C(lit.) and a density of 1.3±0.1 g/cm3. It is listed by 1 supplier; request a quote for pricing. Record last updated Aug 21, 2026.

CAS No.: 370-81-0
Jingsj CID: J-3691-9
Molecular Formula: C₁₄H₂₂N₄O₂
Molecular Weight: 278.350 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	210-214 °C(lit.)
Density	1.3±0.1 g/cm3
Exact Mass	278.174286
PSA	82.92000
LogP	0.85
Refractive Index	1.626

Activity & Biological Data

Additional Information	[1]. Suzuki K, et al. Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone). Am J Pathol. 1969 Feb;54(2):307-25. [2]. Sanadgol N, et al. Alpha-lipoic acid mitigates toxic-induced demyelination in the corpus callosum by lessening of oxidative stress and stimulation of polydendrocytes proliferation. Metab Brain Dis. 2018 Feb;33(1):27-37.

Customs & Trade Information

HS Code	2928000090
Summary	2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Bis(cyclohexanone)oxaldihydrazone?

The CAS number of Bis(cyclohexanone)oxaldihydrazone is 370-81-0.

What are the molecular formula and molecular weight of Bis(cyclohexanone)oxaldihydrazone?

Bis(cyclohexanone)oxaldihydrazone has molecular formula C14H22N4O2 and molecular weight 278.350 g/mol.

Which suppliers offer Bis(cyclohexanone)oxaldihydrazone?

1 supplier(s) listed; request a quote for pricing.

What are the upstream and downstream products of Bis(cyclohexanone)oxaldihydrazone?

For Bis(cyclohexanone)oxaldihydrazone, Upstream Products: Oxalyl dihydrazide, Cyclohexanone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Bis(cyclohexanone)oxaldihydrazone (CAS 370-81-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-3691-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.