Labetalol

拉贝洛尔

Also known as: 2-Hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl}benzamide, AH5158, SCH-15719W, 5-[1-Hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl]salicylamide, Trandate, ibidomide, Albetol, Amipress, Pressalolo, Labrocol, Ipolab, rac Labetalol, (+/-)-Labetalol

Labetalol (CAS 36894-69-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C19H24N2O3 and a molecular weight of 328.405 g/mol. It is also known as 2-Hydroxy-5-{1-hydroxy-2-[(1-methyl-3-phenylpropyl)amino]ethyl}benzamide, AH5158 and SCH-15719W. Key properties include a boiling point of 552.7±50.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 288.1±30.1 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 36894-69-6
Jingsj CID: J-1980042-4
Molecular Formula: C₁₉H₂₄N₂O₃
Chinese Name: 拉贝洛尔
Molecular Weight: 328.405 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	552.7±50.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	288.1±30.1 °C
Exact Mass	328.178680
PSA	95.58000
LogP	2.31
Vapor Pressure	0.0±1.6 mmHg at 25°C
Refractive Index	1.609
Storage Conditions	2-8°C

Activity & Biological Data

Target	α1-adrenergic receptor β-adrenoceptor
Additional Information	[1]. Brogden RN, et al. Labetalol: a review of its pharmacology and therapeutic use in hypertension. Drugs. 1978;15(4):251-270. [2]. Greenslade FC, et al. Labetalol binding to specific alpha- and beta-adrenergic sites in vitro and its antagonism of adrenergic responses in vivo. J Mol Cell Cardiol. 1979 Aug;11(8):803-11. [3]. Easterling T, et al. Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial. Lancet. 2019 Sep 21;394(10203):1011-1021. [4]. Erdtsieck-Ernste EB, et al. Changes in adrenoceptors and monoamine metabolism in neonatal and adult rat brain after postnatal exposure to the antihypertensive labetalol. Br J Pharmacol. 1992 Jan;105(1):37-44. [5]. Johnson JD, et al. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience. 2005;135(4):1295-307.

Target

α1-adrenergic receptor β-adrenoceptor

Additional Information

[1]. Brogden RN, et al. Labetalol: a review of its pharmacology and therapeutic use in hypertension. Drugs. 1978;15(4):251-270. [2]. Greenslade FC, et al. Labetalol binding to specific alpha- and beta-adrenergic sites in vitro and its antagonism of adrenergic responses in vivo. J Mol Cell Cardiol. 1979 Aug;11(8):803-11. [3]. Easterling T, et al. Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial. Lancet. 2019 Sep 21;394(10203):1011-1021. [4]. Erdtsieck-Ernste EB, et al. Changes in adrenoceptors and monoamine metabolism in neonatal and adult rat brain after postnatal exposure to the antihypertensive labetalol. Br J Pharmacol. 1992 Jan;105(1):37-44. [5]. Johnson JD, et al. Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines. Neuroscience. 2005;135(4):1295-307.

Customs & Trade Information

HS Code	2924299090
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Labetalol?

The CAS number of Labetalol is 36894-69-6.

What are the molecular formula and molecular weight of Labetalol?

Labetalol has molecular formula C19H24N2O3 and molecular weight 328.405 g/mol.

What are the upstream and downstream products of Labetalol?

For Labetalol, Downstream Products: 4-Phenylbutan-2-amine.

Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Labetalol (CAS 36894-69-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1980042-4 (accessed 2026-10-28).

Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.