Clozapine N-oxide
Also known as: CNO, 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-oxide, Clozapine N-oxide Methanol Adduct, 8-Chloro-11-(4-methyl-4-oxido-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine, 5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-4-oxido-1-piperazinyl)-
Clozapine N-oxide (CAS 34233-69-7) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C18H19ClN4O and a molecular weight of 342.823 g/mol. Key properties include a melting point of 190-248ºC, a boiling point of 517.4ºC at 760mmHg, a density of 1.36g/cm3 and a flash point of 266.7ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 34233-69-7
- Jingsj CID
- J-1975948-3
- Molecular Formula
- C18H19ClN4O
- Molecular Weight
- 342.823 g/mol
- Category
- Organohalogen Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 190-248ºC |
|---|---|
| Boiling Point | 517.4ºC at 760mmHg |
| Density | 1.36g/cm3 |
| Flash Point | 266.7ºC |
| Exact Mass | 342.124725 |
| PSA | 57.06000 |
| LogP | 0.76 |
| Refractive Index | 1.685 |
| Storage Conditions | 2-8℃ |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | DREADD[1] |
|---|---|
| Additional Information | [1]. Wess J, et al. Novel designer receptors to probe GPCR signaling and physiology. Trends Pharmacol Sci. 2013 Jul;34(7):385-92. [2]. Chang WH, et al. Reversible metabolism of clozapine and clozapine N-oxide in schizophrenic patients. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Jul;22(5):723-39. |
Frequently Asked Questions
What is the CAS number of Clozapine N-oxide?
The CAS number of Clozapine N-oxide is 34233-69-7.
What are the molecular formula and molecular weight of Clozapine N-oxide?
Clozapine N-oxide has molecular formula C18H19ClN4O and molecular weight 342.823 g/mol.
Is Clozapine N-oxide hazardous?
Clozapine N-oxide has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Clozapine N-oxide (CAS 34233-69-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1975948-3 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.