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Bis(2,2,2-trifluoroethyl) ether

Also known as: Fluorothyl, Flurothyl, 1,1,1-trifluoro-2-(2,2,2-trifluoroethoxy)ethane, 2,2,2-Trifluoroethyl ether, Hexafluorodiethyl ether, Indoklon, 1,1'-Oxybis(2,2,2-trifluoroethane)

Bis(2,2,2-trifluoroethyl) ether (CAS 333-36-8) is a compound in the Ethers category listed in the Jingsj chemical database. It has the molecular formula C4H4F6O and a molecular weight of 182.06400 g/mol. Key properties include a boiling point of 62-63 °C(lit.), a density of 1.404 g/mL at 25 °C(lit.) and a flash point of 1.7 °C. It is classified under GHS with signal word Danger and hazard statements H225 — Highly flammable liquid and vapour, H315 — Causes skin irritation and H319 — Causes serious eye irritation. It is listed by 1 supplier; request a quote for pricing. Record last updated Nov 2, 2026.

CAS No.
333-36-8
Jingsj CID
J-22016-1
Molecular Formula
C4H4F6O
Molecular Weight
182.06400 g/mol
Category
Ethers
Last updated
11/2/2026
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Physicochemical Properties

Boiling Point62-63 °C(lit.)
Density1.404 g/mL at 25 °C(lit.)
Flash Point1.7 °C
Exact Mass182.01700
PSA9.23000
LogP2.12760
Refractive Indexn20/D 1.300(lit.)

GHS Safety & Compliance

Flammable / IrritantSignal word: Danger
  • H225 — Highly flammable liquid and vapour
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Gao Y, et al. IL-33 Provides Neuroprotection through Suppressing Apoptotic, Autophagic and NF-κB-Mediated Inflammatory Pathways in a Rat Model of Recurrent Neonatal Seizure. Front Mol Neurosci. 2017 Dec 19;10:423.

Customs & Trade Information

HS Code2909199090
Summary2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Bis(2,2,2-trifluoroethyl) ether?

The CAS number of Bis(2,2,2-trifluoroethyl) ether is 333-36-8.

What are the molecular formula and molecular weight of Bis(2,2,2-trifluoroethyl) ether?

Bis(2,2,2-trifluoroethyl) ether has molecular formula C4H4F6O and molecular weight 182.06400 g/mol.

Which suppliers offer Bis(2,2,2-trifluoroethyl) ether?

1 supplier(s) listed; request a quote for pricing.

Is Bis(2,2,2-trifluoroethyl) ether hazardous?

Bis(2,2,2-trifluoroethyl) ether has GHS signal word Danger and hazard statements H225 — Highly flammable liquid and vapour; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Bis(2,2,2-trifluoroethyl) ether?

For Bis(2,2,2-trifluoroethyl) ether, Upstream Products: Diglycolic acid, 2-Chloro-1,1,1-trifluoroethane, 2,2,2-Trifluoroethanol; Downstream Products: 2,2,2-Trifluoroethyl trifluoroacetate, 2,2,2-Trifluoroethyl formate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Bis(2,2,2-trifluoroethyl) ether (CAS 333-36-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-22016-1 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.