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Salicylidene salicylhydrazide

Also known as: SCS, N'-Salicylidenesalicylic hydrazide, 2-Hydroxybenzylidene 2-hydroxybenzhydrazide, 2-HYDROXYBENZYLIDENE SALICYLHYDRAZIDE, 2-hydroxy-benzoic acid [(2-hydroxyphenyl)methylene]hydrazide, Salicylaldehyde 2-hydroxybenzoylhydrazone, NSC 87864, 2-Hydroxybenzylidene salicylhydrazide, 1-Salicylidene-2-salicyloylhydrazine, 1-Salicyloyl-2-salicylidenehydrazine

Salicylidene salicylhydrazide (CAS 3232-36-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C14H12N2O3 and a molecular weight of 256.25700 g/mol. Key properties include a melting point of 280-284°C, a boiling point of 427.3ºC at 760mmHg, a density of 1.406g/cm3 and a flash point of 212.2ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
3232-36-8
Jingsj CID
J-28052-4
Molecular Formula
C14H12N2O3
Molecular Weight
256.25700 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point280-284°C
Boiling Point427.3ºC at 760mmHg
Density1.406g/cm3
Flash Point212.2ºC
Exact Mass256.08500
PSA81.92000
LogP2.25260
Appearancesolid | off-white
Refractive Index1.615
Additional PropertyDMSO: ~20 mg/mL

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed
  • H319 — Causes serious eye irritation

Activity & Biological Data

TargetIC50: 32 nM (α2β1γ1θ; by VIPR measurement) IC50: 4.5 nM (α2β1γ1θ), 5.3 nM (α2β1γ1), 7.9 nM (α1β1γ2s) (Measured by using whole-cell patch clamp)[1]
Additional Information[1]. Thompson SA, et al. Salicylidene salicylhydrazide, a selective inhibitor of beta 1-containing GABAA receptors. Br J Pharmacol. 2004 May;142(1):97-106. [2]. Rukh L, et al. Efficacy assessment of salicylidene salicylhydrazide in chemotherapy associated peripheral neuropathy. Eur J Pharmacol. 2020 Dec 5;888:173481.

Customs & Trade Information

HS Code2928000090
Summary2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Salicylidene salicylhydrazide?

The CAS number of Salicylidene salicylhydrazide is 3232-36-8.

What are the molecular formula and molecular weight of Salicylidene salicylhydrazide?

Salicylidene salicylhydrazide has molecular formula C14H12N2O3 and molecular weight 256.25700 g/mol.

Is Salicylidene salicylhydrazide hazardous?

Salicylidene salicylhydrazide has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H319 — Causes serious eye irritation.

What are the upstream and downstream products of Salicylidene salicylhydrazide?

For Salicylidene salicylhydrazide, Upstream Products: Salicylaldehyde, Salicylhydrazide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Salicylidene salicylhydrazide (CAS 3232-36-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-28052-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.