Nigericin sodium salt
尼日利亚菌素钠
Also known as: Nigericin sodium salt, Antibiotic K178, Antibiotic X464, Azalomycin M, Helexin C, Helixin C, Polyetherin A, Nigericin monosodium salt, Sodium nigericin, Nigericin, monosodium salt, Nigericin.Na, 2H-Pyran-2-acetic acid, tetrahydro-6-[[(2S,4R,5R,7R,9R,10R)-9-methoxy-2,4,10-trimethyl-2-[(2S,2'R,3'S,5R,5'R)-octahydro-2,3'-dimethyl-5'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl][2,2'-bifuran]-5-yl]-1,6-dioxaspiro[4.5]dec-7-yl]methyl]-α,3-dimethyl-, sodium salt, (αR,2R,3S,6R)- (1:1), Sodium (2R)-2-[(3S,6R)-6-[[(2S,4R,5R,7R,9R,10R)-2-[(5S)-5-[(2R,3S,5R)-5-[(2S,3S,5R,6R)-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyloxan-2-yl]-3-methyloxolan-2-yl]-5-methyloxolan-2-yl]-9-methoxy-2,4,10-trimethyl-1,6-dioxaspiro[4.5]decan-7-yl]methyl]-3-methyloxan-2-yl]propanoate, Nsc292567
Nigericin sodium salt (CAS 28643-80-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C40H67NaO11 and a molecular weight of 746.943 g/mol. It is also known as Antibiotic K178, Antibiotic X464 and Azalomycin M. Key properties include a boiling point of 779.9ºC at 760mmHg, a density of 1.19g/cm3 and a flash point of 226.9ºC. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 28643-80-3
- Jingsj CID
- J-1974515-2
- Molecular Formula
- C40H67NaO11
- Chinese Name
- 尼日利亚菌素钠
- Molecular Weight
- 746.943 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 779.9ºC at 760mmHg |
|---|---|
| Density | 1.19g/cm3 |
| Flash Point | 226.9ºC |
| Exact Mass | 746.458130 |
| PSA | 145.20000 |
| LogP | 4.37090 |
| Vapor Pressure | 4.26E-28mmHg at 25°C |
| Storage Conditions | 2-8°C |
| Additional Property | Soluble in chloroform, methanol or ethanol |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Yakisich JS, et al. Nigericin decreases the viability of multidrug-resistant cancer cells and lung tumorspheres and potentiates the effects of cardiac glycosides. Tumour Biol. 2017 Mar;39(3):1010428317694310 [2]. Bissinger R, et al. Triggering of Suicidal Erythrocyte Death by the Antibiotic Ionophore Nigericin. Basic Clin Pharmacol Toxicol. 2016 May;118(5):381-9 [3]. Deng CC, et al. Nigericin selectively targets cancer stem cells in nasopharyngeal carcinoma. Int J Biochem Cell Biol. 2013 Sep;45(9):1997-2006 [4]. Zhou HM, et al. Suppression of colorectal cancer metastasis by nigericin through inhibition of epithelial-mesenchymal transition. World J Gastroenterol. 2012 Jun 7;18(21):2640-8 |
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Frequently Asked Questions
What is the CAS number of Nigericin sodium salt?
The CAS number of Nigericin sodium salt is 28643-80-3.
What are the molecular formula and molecular weight of Nigericin sodium salt?
Nigericin sodium salt has molecular formula C40H67NaO11 and molecular weight 746.943 g/mol.
Is Nigericin sodium salt hazardous?
Nigericin sodium salt has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
Data compiled from public chemical databases and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Nigericin sodium salt (CAS 28643-80-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-1974515-2 (accessed 2026-10-28).
Data for reference only; verify specifications, grades and regulatory status with suppliers before purchase.